Results 41 to 50 of about 1,555,661 (215)

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Preliminary findings on the psychometric properties of the ICAST-home among children in Southeast Nigeria

Child Protection and Practice
Background: Child abuse is a significant global public health issue, with a high prevalence in Southeast Nigeria. Developing and evaluating screening tools that are sensitive and specific to local conditions is critical.
Elekwachi Chimezie Lekwas, Peter Onyekwere Ebigbo, John Eze, Obi Ikechukwu, Doris Chinelo Eyisi   +4 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Development and Evaluation of the Family Asset Builder: A New Child Protective Services Intervention to Address Chronic Neglect

Journal of Family Strengths, 2014
Over the past 20 years, neglect has been the most pervasive form of child maltreatment in the United States, affecting more than half a million children annually. Further, neglect is more likely than other forms of maltreatment to occur repeatedly within
Tyler W Corwin, Erin J Maher, Monica Idzelis Rothe, Maggie Skrypek, Caren Kaplan, Dan Koziolek, Brenda Mahoney   +6 more
doaj   +1 more source

Effects of attention-deficit/hyperactivity disorder on child abuse and neglect

, 2022
It is known that children with mental and developmental problems are at risk of abuse and neglect. Attention-deficit/hyperactivity disorder is one of the most frequent neurodevelopmental disorders in children and adolescents. The purpose of this study is
Uzun, Mehmet Erdem, Gokten, Emel Sari, Duman, Nagihan Saday, SOYLU, Nusret   +3 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Youth Perspectives of Neglect Signs and Help-Seeking

Behavioral Sciences
Child neglect, recognized as the most prevalent form of child maltreatment with profound repercussions on children’s development, has received limited scholarly attention compared to abuse.
Ayala Cohen, Ibtisam Marey-Sarwan, Daphna Gross Manos   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Drawing the Line: An Exploration of How Lay People Construct Child Neglect [PDF]

This thesis uses a Foucauldian approach to explore how lay people construct child neglect in England. The concept of child neglect developed after the Industrial Revolution in conjunction with the construction of ‘normal’ childhood.
Williams, Sasha
core   +3 more sources