Results 51 to 60 of about 1,555,661 (215)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
BMJ Paediatrics OpenBackground This study explores child welfare investigations for medical neglect in Canada, focusing on household, family and child characteristics and drivers of substantiated victimisation.Methods Data from the Canadian Incidence Study of Reported Child
Barbara Fallon +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Commission to Eliminate Child Abuse and Neglect Fatalities [website]
, 2016 This website describes the history and activities of the Commission to Eliminate Child Abuse and Neglect Fatalities, established in 2012 by legislative mandate. It includes documentation and a final report that addresses the Commission's recommendations
United States. Commission to Eliminate Child Abuse and Neglect Fatalities.
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Risk factors for child physical abuse and neglect among Chinese young mothers
, 2017 Although studies have reported a linkage between young pregnancy and child maltreatment risk, it is still unclear about what factors place young mothers at greater risk of maltreating their child in Chinese context.
Tsang, A +31 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Early childhood caries: Exploring the ethical implications for dental neglect in South Africa
Health SA Gesondheid: Journal of Interdisciplinary Health SciencesBackground: Dental neglect is defined as the ‘wilful’ failure of a parent and/or guardian to provide optimal oral healthcare, leading to pain and infection. Child abuse and neglect, including dental neglect, are significant public health issues with long-
Nashna Rampersad, Nadia Mohamed
doaj +1 more source
Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: September 24, 2015
, 2015 Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on September 24, 2015. This meeting includes opening remarks from Chairman Sanders, reactions to the revised National Strategy, and a ...
CQ Transcriptions
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Performing child neglect in social work practice [PDF]
, 2013 Informed by Foucauldian and feminist theoretical positions, the study explores how child neglect is 'performed' by social work professionals and service users.
CASEY, BETH,ANNE
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