Results 71 to 80 of about 1,555,661 (215)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: January 16, 2016

open access: yes, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on January 16, 2016.
CQ Transcriptions
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: February 14, 2016

open access: yes, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on February 14, 2016.This meeting includes deliberation on recommendations for the Commission's final report to the President and ...
CQ Transcriptions
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: December 3, 2015

open access: yes, 2015
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on December 3, 2015. This meeting includes recommendations by the American Indian/Alaska Native subcommittee and the Disproportionality ...
CQ Transcriptions
core  

Suspected child abuse and neglect reporting behaviour [PDF]

open access: yes, 2003
Executuve Summary\ud Background and Aims\ud Child abuse and neglect is a tragedy within our community, with over 10,000 substantiated reports of abuse and neglect in Queensland in the past year.
Schweitzer, Robert   +3 more
core  

Safeguarding children in dentistry: 1. Child protection training, experience and practice of dental professionals with an interest in paediatric dentistry [PDF]

open access: yes, 2009
* Few dental professionals with child protection training have experience of making referrals. * There is a wide gap in practice between recognising signs of child abuse and neglect and responding effectively.
Sidebotham, Peter   +11 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: January 28, 2016

open access: yes, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on January 28, 2016. This meeting includes deliberation on recommendations for the Commission's final report to the President and ...
CQ Transcriptions
core  

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