Results 51 to 60 of about 113,034 (255)
Decomposing Child Poverty Reduction [PDF]
European Journal of Social Security, 2014 European countries vary in the extent to which they succeed in reducing poverty using social transfers. However, we do not have good ways of understanding how these different outcomes are achieved. It is therefore very difficult to learn lessons from abroad.
Bradshaw, J., Huby, M.
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Contraception and Reproductive MedicineIntroduction Little research has focused on measuring free contraceptive choice, or whether individuals can make decisions about contraception without barriers or coercion.
Brooke W. Bullington +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Book review: Child Poverty: Aspiring to Survive by Morag C Treanor
Scottish Journal of Residential Child Care, 2021 Aspiring to Survive was published in February of 2020, at the precipice of the Covid-19 pandemic which has impacted every aspect of our lives and shone a harsh light on the inequalities in our society, as well as exacerbating them. In Aspiring to Survive,
Kate Mackinnon, Rosie Moore
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Revija za socijalna politika, 2020 The objective of this paper is to estimate the expected effects of the pandemic of Covid-19 for child poverty in North Macedonia. We rely on MK-MOD Tax & Benefit Microsimulation Model for North Macedonia based on the Survey on Income and Living ...
Marjan Petreski
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source