Results 121 to 130 of about 4,321,176 (343)

Climate Action and the UNCRC: A ‘Postpaternalist’ World Where Children Claim Their Own Rights

open access: yesYouth
In this paper, it is argued that we are in a ‘postpaternalist’ era for children’s rights, involving grassroots action from children (for the first time, on a global scale) rather than well-meaning adults ‘giving’ children their rights.
Aoife Daly   +7 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Beyond Paternalism: The Role of Counsel for Children in Abuse and Neglect Proceedings [PDF]

open access: yes, 2013
[Excerpt] “Across the nation, lawyers routinely represent children who enter the juvenile court system. Juvenile court systems typically handle two types of cases: delinquency and dependency.
Malempati, Suparna
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Engaging East Harlem, New York youth in action gun violence prevention research and child rights: a preliminary study. [PDF]

open access: yesInj Epidemiol, 2023
Malla P   +11 more
europepmc   +1 more source

International Laws of War and the African Child: Norms, Compliance, and Sovereignty [PDF]

open access: yes
The Convention on the Rights of the Child of 1989 is one of the most prominent international humanitarian treaty in world history. It entered into force quicker than any other treaty and currently only two countries (the United States and Somalia) have ...
Jeffrey Herbst
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Child feeding and human rights.

open access: yesInternational breastfeeding journal, 2006
The human right to adequate food needs to be interpreted for the special case of young children because they are vulnerable, others make the choices for them, and their diets are not diverse. There are many public policy issues relating to child feeding.The core of the debate lies in differences in views on the merits of infant formula.
openaire   +3 more sources

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