Results 111 to 120 of about 238,524 (311)

The European Court of Human Rights and the Hague Child Abduction Convention:prioritising return or reflection? [PDF]

open access: yes, 2015
Over the last four decades the 1980 Hague Convention has provided for the prompt return of children to their State of habitual residence. But now that wrongful removals and retentions are most often carried out by primary carers, the majority of whom ...
McEleavy, Peter, Peter McEleavy
core   +1 more source

Climate Action and the UNCRC: A ‘Postpaternalist’ World Where Children Claim Their Own Rights

open access: yesYouth
In this paper, it is argued that we are in a ‘postpaternalist’ era for children’s rights, involving grassroots action from children (for the first time, on a global scale) rather than well-meaning adults ‘giving’ children their rights.
Aoife Daly   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Engaging East Harlem, New York youth in action gun violence prevention research and child rights: a preliminary study. [PDF]

open access: yesInj Epidemiol, 2023
Malla P   +11 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Article 2 of the United Nations Convention on the Rights of the Child: Non-Discrimination and Children’s Rights [PDF]

open access: yes, 2019
Non-discrimination is a fundamental principle of human rights law and is embraced in Article 2 of the United Nations Convention on the Rights of the Child.
Sutherland, Elaine E
core  

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