Results 91 to 100 of about 187,238 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Integrating child rights standards in contraceptive and abortion care for minors in Africa. [PDF]
Int J Gynaecol Obstet, 2022 Kangaude GD +3 more
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
THE IMPORTANCE OF COLLABORATION BETWEEN THE SOCIAL WORKER AND THE CHILD RIGHTS PROTECTION SPECIALIST
Social Inquiry into Well-BeingThis article analyses the importance of collaboration between the social worker and the child rights protection specialist. In order for good-quality social services to be provided to families and children in a timely manner, collaboration between ...
Vida Gudžinskienė, Ina Jasiukonienė
doaj +1 more source
"Reverse innovation" and "child rights" in further school health promotion. [PDF]
Pediatr Int, 2022 Kobayashi J, Takahashi K.
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Early Lift of Restrictions in Mongolia During the COVID-19 Pandemic: Child Rights, Public Trust, and Social Inequality. [PDF]
Asia Pac J Public Health, 2022 Dorjdagva J, Batbaatar E, Kauhanen J.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source