Results 91 to 100 of about 3,688,087 (301)
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Child labor, education, and children's rights [PDF]
Child labor is widespread, and bad for development, both that of the individual child, and of the society and economy in which she, or he lives. If allowed to persist to the current extent,child labor will prevent the achievement of the Millennium ...
Fares, Jean +3 more
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The impact of the rule of law on the implementation of the convention on the rights of the child in Indonesia and Australia [PDF]
, 2009 This thesis concerns the implementation of the Convention on the Rights of the Child (‘the CRC’) in Indonesia: The chasm between theory and practice.
Susantijo, Susi
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Acta Universitatis Lodziensis Folia Iuridica, 2016 Children’s rights are one of the most important and challenging international and national regulations. The Convention on the Rights of the Child as well as the Polish law explicitly stipulate that the best interest of the child has to be taken as ...
Karolina Mendecka
doaj +1 more source
Croatian Journal of Education : Hrvatski časopis za odgoj i obrazovanje, 2014 In this paper the author elaborates the issue of the child's right to play through the UN Convention on the Rights of the Child. As the three main challenges she puts forth the questions of recognition, respect and promotion of children's right to play. Referring to the studies which indicate that the time children spend playing is getting shorter, she
openaire +4 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Child Participatory Rights in the Arab World [PDF]
, 2003 This paper discusses child rights advocacy in the Arab world which can be frustrated by unequal development, religion-state nexus, continuing conflicts and a democratic deficit in the region.
Sait, Siraj
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Financing child rights in Malawi. [PDF]
BMC Public Health, 2023 Etter-Phoya R +9 more
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Child victims in the crown court [PDF]
, 2000 This thesis intends to critically examine how a child victim of abuse is dealt with during a Crown Court trial. In trials for child abuse the victim would normally be the main prosecution witness, and so undoubtedly would be called to give evidence ...
Gillespie, Alisdair A.
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