Results 71 to 80 of about 3,688,087 (301)

COMMENT– The Role of Courts in Safeguarding the Best Interest of the Child (Amharic)

open access: yesMizan Law Review, 2019
The best interest of the child is a multifaceted principle governing children’s rights. This principle is tri-dimensional which serves as (i) human right, (ii) a mechanism of evaluation of other rights, and (iii) as a means of interpreting other rights ...
Abreha Mesele, Mekonnen Nigussie
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Right of Child Victims of Armed Conflict to Reintegration and Recovery

open access: yesPotchefstroom Electronic Law Journal, 2012
Article 39 of the Convention on the Rights of the Child provides for the right to recovery and reintegration of child victims of armed conflict. In this publication an explanation is tendered of when children are considered to be victims of armed ...
JA Robinson
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Children's rights the rights of children and their families who need or are receiving community services.

open access: yes, 2006
Title from cover (i.e. p. [1]) of PDF document (viewed July 28, 2006).; "This publication was produced by Ohio Legal Rights Service through a contract with National Alliance on Mental Illness (NAMI) Ohio and with funding from the Ohio Department of ...
Ohio Legal Rights Service.
core  

Eliminating child labour: what needs to be done?

open access: yesBMJ Paediatrics Open, 2023
Ramya Subrahmanian
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Children’s rights organizations in Sweden and their relation to public child welfare

open access: yesNordic Social Work Research
This paper presents a mapping of the Swedish children’s rights organizations (SCROs) and an analysis of how these organizations relate to public child welfare. SCROs represent a children’s rights discourse and are active as voice and service producers in
Hedvig Nylén
doaj   +1 more source

From the Publications Chair

open access: yesJournal of Childhood Studies, 2011
On the (Complex) Topic of Chidren's Rights The Convention on the Rights of the Child sets out the rights that must be realized for children to develop their full potential, free from hunger and want, neglect and abuse.
Iris Berger
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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