Results 51 to 60 of about 238,524 (311)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Save the Children’s work on child protection and child rights in Mozambique and South Sudan
, 2023 Background Save the Children Norway (SCN) and its partners are implementing an extensive programme to support children’s education, child protection and child rights in 16 countries. The programme is running from 2019 through 2023 and is funded by the
Gichohi, Matthew, Mæstad, Ottar
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The impact of the Ebola epidemics on children’s rights: a scoping review
Global Health Action, 2022 Background The Ebola virus is known as one of the deadliest pathogens to infect humans. Children represent a minority of Ebola Virus Disease cases globally.
Irene Lunghi +8 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2023 reservedThe objective of this research is to conduct a thorough assessment of the human rights framework in Kyrgyzstan and explore strategies to empower child advocacy efforts, thereby enhancing the realization of children's rights.
AMANALIEVA, KANYKEI
core
New public-centered child protection system in Korea [PDF]
Clinical and Experimental Pediatrics, 2023 We Sun Shim
doaj +1 more source
Considerations for child protection and practice: What is child protection now?
Child Protection and PracticeOver the last 50 years, the global community has forged consensus on child rights and, thereby, laid the basis for defining child protection in terms of three cornerstones: (1) the protection from all forms of violence in all settings and contexts and ...
Christine Wekerle
doaj +1 more source
Adolescents’ Notions About Children’s Rights
Российский психологический журнал, 2018 Introduction. The studies on children’s rights actualize the unity of the external and internal. The external means social environment which interacts with the subject.
Anna V. Chernaya, Lyudmila N. Grishina
doaj +1 more source