Results 21 to 30 of about 26,400 (257)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Intersections between Human Trafficking and Education: Toward New Research Agendas
Journal of Contemporary Issues in Education, 2021 Human trafficking is a social issue that has gained attention in the media and in scholarship. A growing number of anti-trafficking organizations and actors have begun to use education to diverse ends. Although not often associated with human trafficking,
Bob Spires
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Human Trafficking in Thailand in Perspective of Human Rights Law
Journal of Law and Legal Reform, 2021 Trafficking in human beings is increasingly due to the greatest gain of the perpetrators. Human trafficking is a global humanitarian problem. With the involvement of many countries, both as a country of origin, destination and transit country, making ...
Natalia Sihotang, Channarong Wiriya
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Social SciencesDespite the improvements in enhanced child protection, there is an increasing concern about the vulnerability and cases of child trafficking in Spain, the southern gateway to Europe from the African continent.
Raquel Verdasco Martínez +3 more
doaj +1 more source
Child Labor Trafficking in the United States: A Hidden Crime
Social Inclusion, 2017 Emerging research brings more attention to labor trafficking in the United States. However, very few efforts have been made to better understand or respond to labor trafficking of minors.
Katherine Kaufka Walts
doaj +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
EXPLODING THE ROLE OF RELIGIOUS INSTITUTIONS IN COMBATING CHILD TRAFFICKING IN NIGERIA
Mimbar Hukum, 2015 Human trafficking is a global challenge especially in the 21stCentury. Nigeria like most developing countries is doing its best in addressing the menace of child trafficking. In view of the fact that religious institutions are highly respected in Nigeria,
Alhaji Umar Alkali +2 more
doaj +3 more sources
Societies, 2022 Brazil has seen a rise in children in narco-trafficking due to increased conflicts between factions and local law enforcement. Mainstream media and scholars tend to frame actions of these factions as organized crime, ignoring the generalized violence the
Veridiana Bessa Franciozo Diniz +1 more
doaj +1 more source