Results 31 to 40 of about 26,400 (257)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Knowledge of and Attitudes toward Child Trafficking in Wolaita Sodo, Southern Ethiopia: Insights from the Origin Community

African Human Mobility Review
Child trafficking is a serious violation of children’s rights under international law, particularly the United Nations Convention on the Rights of the Child (UNCRC).
Tigist Solomon, Darge Wole, Abebaw Minaye   +2 more
doaj   +1 more source

THE ROLE OF THE SOCIAL WORKER IN THE PREVENTION OF CHILD TRAFFICKING IN SOUTH AFRICA

Social Work/Maatskaplike Werk, 2012
According to the United Nations Palermo Protocol (2000:14), child trafficking is defined as the recruitment, transportation, transfer, harbouring or receipt of children through threats, force, coercion, abduction, fraud and/or deception.
Juliet Patience Sambo, Gloudien Spies
doaj   +1 more source

Human trafficking and surrogate motherhood: challenges

Конституційно-правові академічні студії, 2021
  Owing to modern scientific advances prospective parents, among other opportunities, enjoy the opportunity, which has not been available before. It consists in giving birth to a child by using another woman’s reproductive capacity when the situation
Viktor Checherskiy
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Orphanage tourism and orphanage volunteering: implications for children

Frontiers in Sustainable Tourism, 2023
Orphanage tourism refers to visits or volunteering in orphanages as part of a holiday or tourist experience. Orphanage tourism is a consumer product which represents the intersection of the desire of orphanage operators to gain access to international ...
Kathryn E. van Doore, Rebecca Nhep, Rebecca Nhep   +2 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Representation of Child Exploitation in the Film 'Trade of Innocents' and Reflections for Indonesia

ASEAN Social Work Journal
The film Trade of Innocents (2012) presents an overview of the situation of child trafficking in Cambodia. It explores the psychological impact of victims and the role of social support interventions in victim recovery, as well as strategies in the ...
Wahyu Pratama Tamba, Muhammad Soekarni, Debrina Vita Ferezagia   +2 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A child-centered approach to trauma- and violence-informed interventions with children who have experienced sex trafficking: Qualitative findings from emergency department providers in Ontario, Canada

Child Protection and Practice
More than 60 % of people who have experienced sex trafficking access an emergency department (ED) for trafficking-related concerns while they are being exploited.
Rebecca Balasa, Momina Khan, Dionne Gesink, Lisa Forman, Corry Azzopardi, Amaya Perez-Brumer   +5 more
doaj   +1 more source