Results 101 to 110 of about 15,284,221 (342)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Personalised lifestyle intervention for shiftworkers with Type 2 Diabetes: a feasibility study and process evaluation

Safety and Health at Work, 2022
Martine van Egmond, Zeena Harakeh, Wilma Otten, Noortje Wiezer   +3 more
doaj   +1 more source

Access to water, women's work and child outcomes [PDF]

Poor rural women in the developing world spend considerable time collecting water. How then do they respond to improved access to water infrastructure? Does it increase their participation in income earning market-based activities?
Koolwal, Gayatri, van de Walle, Dominique   +1 more
core  

Child Labour in the Russian Federation [PDF]

, 2002
Working paper on child labor written in 2002 for the ILO by Svetlana Stephenson, in preparation of the ILO Declaration entitled A Future Without Child Labour, under the mandate of the ILO Declaration on Fundamental Principles and Rights at ...
International Labour Office, Stephenson, Svetlana   +1 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Family, school and neighborhood factors moderating the relationship between physical activity and some aspects of mental health in adolescents

International Journal of Occupational Medicine and Environmental Health, 2019
The impact of physical activity on mental health is widely described in literature. Less attention is given to factors which may modify this correlation, except for gender.
Dorota Kleszczewska, Joanna Mazur, Jadwiga Siedlecka   +2 more
doaj   +1 more source

Longitudinal study of local authority child and family social workers (wave 1) Findings from a 5 year study of local authority child and family social workers in England. [PDF]

, 2019
The longitudinal study investigates recruitment, retention and career progression in local authority child and family social work over 5 years. This is the first of 5 reports.
Coburn, S, DfE, Felton, J, IFF, Johnson, C, McCaughan, S, McLaughlin, H, Pollock, S, Sanders-Earley, A, Scholar, HF, Winterbotham, M   +10 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Mobilizing agencies for incidence surveys on child maltreatment: successful participation in Switzerland and lessons learned

Child and Adolescent Psychiatry and Mental Health, 2018
Background Many countries around the world lack data on the epidemiology of agency response to child maltreatment. They therefore lack information on how many children in need get help and protection or if children stand equal chances across regions to ...
Andreas Jud, Céline Kosirnik, Tanja Mitrovic, Hakim Ben Salah, Etienne Fux, Jana Koehler, Rahel Portmann, René Knüsel   +7 more
doaj   +1 more source