Results 141 to 150 of about 817,148 (269)

Effectiveness of a training programme on frontline workers' skills and competencies in promoting safe and stable nurturing relationships: A quasi-experimental study from rural central India. [PDF]

Indian J Med Res
Trimukh Parsure A, Gupta SS, Jakasania A, Kothekar P, Sathe H, Giri M.   +5 more
europepmc   +1 more source

Early childhood and childhood [PDF]

, 2016
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Oxidized vitamin E metabolites during infancy and childhood asthma risk: too little, too much, or just right? [PDF]

Am J Respir Crit Care Med
Turi KN, Gebretsadik T, Rosas-Salazar C, Hartert TV.   +3 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The long reach of childhood income inequality: a multinational twin study of gene-environment interplay on adult depressive symptoms. [PDF]

Psychol Med
Petkus AJ, Reynolds CA, Finch BK, Thomas K, Beam CR, Catts VS, Ericsson M, Finkel DG, Franz CE, Kremen WS, Larsen LA, Martin NG, McGue M, Mosing MA, Neiderhiser JM, Nygaard M, Pedersen NL, Thalamuthu A, Whitfield KE, Gatz M, IGEMS Consortium.   +20 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Association Between Childhood Trauma and Prodromal Psychotic Symptoms in Nursing Undergraduates: Mediating Roles of Depression and Anxiety. [PDF]

J Multidiscip Healthc
Wang Y, Cai Q, Xu X, Gu J.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Childhood emotional abuse and adolescent anxiety: a moderated mediation model of bullying victimization, perceived teacher legitimacy, and negative legal emotion. [PDF]

Front Psychol
Wang S, Sun W, Hong Z, Huang H, Xu S.
europepmc   +1 more source