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Therapeutic Options for Childhood Absence Epilepsy [PDF]

Pediatric Reports, 2021
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years.
Victoria Elisa Rinaldi, Giuseppe Di Cara, Elisabetta Mencaroni, Alberto Verrotti   +3 more
doaj   +5 more sources

Dysfunction of the glymphatic system in childhood absence epilepsy [PDF]

Frontiers in Neuroscience, 2023
ObjectiveThis study aimed to evaluate the glymphatic system in childhood absence epilepsy (CAE) using diffusion tensor image analysis along the paravascular space (DTI-ALPS) index.
Wanqing Pu, Shanzhen Wei, Mengdi Qiu, Xiaoyu Chen, Wenwei Zou, Yingchao Ge, Wenchao Qiu   +6 more
doaj   +4 more sources

Impaired rich-club connectivity in childhood absence epilepsy [PDF]

Frontiers in Neurology, 2023
IntroductionChildhood absence epilepsy (CAE) is a well-known pediatric epilepsy syndrome. Recent evidence has shown the presence of a disrupted structural brain network in CAE. However, little is known about the rich-club topology.
Yadong Yu, Mengdi Qiu, Wenwei Zou, Ying Zhao, Yan Tang, Jisha Tian, Xiaoyu Chen, Wenchao Qiu   +7 more
doaj   +4 more sources

Functional brain network characteristics are associated with epilepsy severity in childhood absence epilepsy [PDF]

NeuroImage: Clinical, 2020
While cognitive impairments are not generally considered to be part of the childhood absence epilepsy (CAE) syndrome, some recent studies report cognitive, mainly attentional, deficits. Here we set out to investigate the whole brain functional network of
Gerhard S. Drenthen, PhD, Floor Fasen, MSc, Eric L.A. Fonseca Wald, MD, PhD, Walter H. Backes, PhD, Albert P. Aldenkamp, PhD, R. Jeroen Vermeulen, MD, PhD, Mariette Debeij-van Hall, MD, PhD, Jos Hendriksen, PhD, Sylvia Klinkenberg, MD, PhD, Jacobus F.A. Jansen, PhD   +9 more
doaj   +3 more sources

A 6-year-old with childhood absence epilepsy and motor hyperactivity [PDF]

Epilepsy & Behavior Reports
A case study of a child with childhood absence epilepsy and hyperactivity introduces the discussion around the psychiatric diagnosis, differential considerations, and pharmacologic treatment options for ADHD/hyperactivity in children with epilepsy.
Stéphane Auvin
doaj   +3 more sources

Co-occurrence of childhood absence epilepsy and self-limited focal epilepsy interictal discharges: Differences from childhood absence epilepsy alone. [PDF]

Epileptic Disord
AbstractObjectiveSome children with Childhood Absence Epilepsy (CAE) exhibit focal abnormalities similar to those observed in Self‐Limited Focal Epilepsies of Childhood (SeLFEs). It remains unclear whether this subgroup of patients may present distinct clinical characteristics or prognoses compared to those with CAE and generalized discharges alone. In
Barbagallo G, Nobile G, Calevo MG, Prato G, Nobili L, Canale E, Mancardi MM.   +6 more
europepmc   +5 more sources

Second monotherapy in childhood absence epilepsy. [PDF]

Neurology, 2017
To determine optimal second monotherapy for children with childhood absence epilepsy (CAE) experiencing initial treatment failure.Children with CAE experiencing treatment failure during the double-blind phase of a randomized controlled trial comparing ethosuximide, valproic acid, and lamotrigine were randomized to open-label second monotherapy with one
Cnaan A, Shinnar S, Arya R, Adamson PC, Clark PO, Dlugos D, Hirtz DG, Masur D, Glauser TA, Childhood Absence Epilepsy Study Group.   +9 more
europepmc   +6 more sources

Feasibility of a mobile cognitive intervention in childhood absence epilepsy [PDF]

Frontiers in Human Neuroscience, 2016
Children with childhood absence epilepsy (CAE) frequently present with cognitive comorbidities and school performance concerns. The present study evaluated the feasibility of an intervention for such comorbidities using a mobile cognitive therapy ...
Peter Glynn, Soyong Eom, Soyong Eom, Frank Zelko, Frank Zelko, Sookyong Koh   +5 more
doaj   +4 more sources

Perampanel and childhood absence epilepsy: A real life experience [PDF]

Frontiers in Neurology, 2022
ObjectivesThe aim of our study was to evaluate the effectiveness and tolerability of perampanel (PER) as first add-on and as second line monotherapy in subjects with childhood absence epilepsy.MethodsOur sample consisted of 20 patients with childhood ...
Francesca Felicia Operto, Alessandro Orsini, Gianpiero Sica, Chiara Scuoppo, Chiara Padovano, Valentina Vivenzio, Valeria de Simone, Rosetta Rinaldi, Gilda Belfiore, Roberta Mazza, Salvatore Aiello, Luigi Vetri, Serena Donadio, Angelo Labate, Grazia Maria Giovanna Pastorino   +14 more
doaj   +2 more sources

Long-term Prognosis of Childhood Absence Epilepsy. [PDF]

Noro Psikiyatr Ars, 2023
We aimed to investigate the long-term prognosis of childhood absence epilepsy (CAE), and identify factors associated with treatment outcomes.Patients with a definitive diagnosis of CAE according to the International League Against Epilepsy 2021 criteria and with a minimum of 3-year follow-up duration were included.
Yaşgüçlükal MA, Özçelik EU, Deniz Elmali A, Çokar Ö, Demirbilek V.   +4 more
europepmc   +3 more sources