Results 61 to 70 of about 140,392 (307)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Psychological Status in Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study [PDF]

Journal of Clinical Oncology, 2009
Psychological quality of life (QOL), health-related QOL (HRQOL), and life satisfaction outcomes and their associated risk factors are reviewed for the large cohort of survivors and siblings in the Childhood Cancer Survivor Study (CCSS). This review includes previously published manuscripts that used CCSS data focused on psychological outcome measures ...
Lonnie K, Zeltzer, Christopher, Recklitis, David, Buchbinder, Bradley, Zebrack, Jacqueline, Casillas, Jennie C I, Tsao, Qian, Lu, Kevin, Krull   +7 more
openaire   +2 more sources

Bone health in childhood cancer: review of the literature and recommendations for the management of bone health in childhood cancer survivors.

Annals of Oncology, 2019
In the past decades, new cancer treatment approaches for children and adolescents have led to a decrease in recurrence rates and an increase in long-term survival.
G. Marcucci, G. Beltrami, A. Tamburini, J. Body, C. Confavreux, Peyman Hadji, G. Holzer, D. Kendler, N. Napoli, N. Napoli, D. Pierroz, R. Rizzoli, M. Brandi   +12 more
semanticscholar   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Auditory complications in childhood cancer survivors: A report from the childhood cancer survivor study [PDF]

Pediatric Blood & Cancer, 2011
AbstractBackgroundStudies have found associations between cancer therapies and auditory complications, but data are limited on long‐term outcomes and risks associated with multiple exposures.ProcedureThe Childhood Cancer Survivor Study is a retrospective cohort investigating health outcomes of long‐term survivors (5+ years) diagnosed and treated ...
Kimberly, Whelan, Kayla, Stratton, Toana, Kawashima, Wendy, Leisenring, Susan, Hayashi, John, Waterbor, Julie, Blatt, Charles A, Sklar, Roger, Packer, Pauline, Mitby, Leslie L, Robison, Ann C, Mertens   +11 more
openaire   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Patients’, parents’, and survivors’ perspective about AI applications in pediatric oncology

EJC Paediatric Oncology
Patients, parents and survivors of childhood cancer are those who represent the critical link between the clinical and technical research spheres.
Hyseni Bocolli Albina, Schneider Carina, Bastos Pais Teresa, Willi Michaela, Brunmair Mattias   +4 more
doaj   +1 more source

A Population-Based Study of COVID-19 Infection Among Childhood Cancer Survivors

Frontiers in Medicine, 2021
Childhood cancer survivors are known to be at risk of chronic co-morbidities, although their risk of COVID-19 infection remains uncertain. Understanding the risk of COVID-19 in this population is necessary to counsel survivors and inform potential ...
Mohammad Agha, Mohammad Agha, Felicia Leung, Rahim Moineddin, Rahim Moineddin, Nicole M. Bradley, Paul J. Gibson, Paul J. Gibson, David C. Hodgson, David C. Hodgson   +9 more
doaj   +1 more source

Secondary Sarcomas in Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study [PDF]

JNCI Journal of the National Cancer Institute, 2007
Childhood cancer survivors are at increased risk for the development of secondary sarcomas. Exposure to radiation therapy is a known risk factor for the development of these sarcomas. Other risk factors for secondary sarcomas have not been well described for childhood cancer survivors.
Tara O, Henderson, John, Whitton, Marilyn, Stovall, Ann C, Mertens, Pauline, Mitby, Debra, Friedman, Louise C, Strong, Sue, Hammond, Joseph P, Neglia, Anna T, Meadows, Leslie, Robison, Lisa, Diller   +11 more
openaire   +2 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source