Results 241 to 250 of about 414,419 (312)

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

Advanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin, Hongru Wang, Yi Yang, Yuhang Xie, Yuan Zhang, Zhiye Du, Yi Huang, Wei Guo, Yang Li, Shidong Wang   +9 more
wiley   +1 more source

Homozygous variegate porphyria: Two cases misdiagnosed as erythropoietic protoporphyria. [PDF]

Mol Genet Metab Rep
Wang C, Bensaber N, Rebeiz L, Tran B, Tortorelli S, Kyle K, Yalom LK, Moghe A, Anderson KE, Leaf RK, Yeung AK.   +10 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Determinants of untimely receipt and non-receipt of routine childhood immunisation in Ebonyi state based on the Adapted Omale INDEPT FORCIS Framework and recommendations for policy and practice: a qualitative study. [PDF]

BMJ Open
Omale UI, Iwegbulam CC, Ekwuazi LC, Amuzie CI, Ikegwuonu CO, Nkwo GE, Ewah RL.   +6 more
europepmc   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Double burden of malnutrition by mid-childhood in an Indian birth cohort: a longitudinal study (2010-2021). [PDF]

Lancet Reg Health Southeast Asia
Yilmaz B, Mohan VR, John S, Kang G, Jebasingh F, Thomas N, Sonawane M, Kolthur-Seetharam U, Koshy B.   +8 more
europepmc   +1 more source

Adverse childhood experiences and risk of non-mental medical diseases in adulthood: an umbrella review. [PDF]

EClinicalMedicine
Valiente-Gómez A, Bücker J, Fontana-McNally M, Gatto DL, Guinart D, Moreno-Alcázar A, Rodríguez CC, de Córdoba Gil C, Padberg F, Torner HP, Radua J, Pérez-Solà V, Fusar-Poli P, Vilajosana E, Hogg B, Rosa AR, Amann BL.   +16 more
europepmc   +1 more source

The respiratory microbiome influences the occurrence of respiratory diseases in children. [PDF]

Front Pediatr
Zheng K, Zhou SH, Liao S, Mu J, Han ZB, Wang B.   +5 more
europepmc   +1 more source

Childhood famine exposure and the risk of gastrointestinal diseases in old individuals: a retrospective cohort analysis using the CHARLS database. [PDF]

BMC Public Health
Yang Q, Rong Z.
europepmc   +1 more source

Associations between socioeconomic status and adverse childhood experiences with multidimensional healthy aging: findings from ELSI-Brazil. [PDF]

BMC Public Health
Ribeiro F, Buscicchio G, Ferreira H, Leist AK.   +3 more
europepmc   +1 more source