Results 11 to 20 of about 777,243 (151)

Thymoma with Myasthenia Gravis in Adolescent [PDF]

Online Journal of Health & Allied Sciences, 2011
Thymomas are exceedingly rare in the first 20 years of life, Thymic lesions comprise approximately 2–3% of all pediatric mediastinal tumors and include thymic cysts, hyperplasia, carcinoma, and thymomas.
Prasad K Shetty,, Balaiah K,, Ganesh Nayak,, Prasanna K Shetty,   +3 more
doaj   +1 more source

A novel DOK7 mutation causing congenital myasthenic syndrome with limb-girdle weakness: case series of three family members

Heliyon, 2021
Congenital myasthenia syndrome (CMS) is a group of heterogeneous diseases affecting the neuromuscular endplate. CMS has a considerably different phenotypic presentations, with the onset time ranging from early infancy to late adulthood. Here, we report a
Mohammed S. Alsallum, Aysha Alshareef, Ahmad R. Abuzinadah, Ahmed K. Bamaga, Ashraf Dallol   +4 more
doaj   +1 more source

Anti-MuSK antibody positive myasthenia gravis with childhood onset [PDF]

Romanian Journal of Neurology, 2016
Myasthenic syndromes are acquired diseases which unite the impairment of neuromuscular transmission with associated muscle weakness, occasional positive anti-acetylcholine or MuSK antibodies and characteristic electrodiagnostic features.
Diana Epure, Smaranda Nita, Raluca Ioana Teleanu   +2 more
doaj   +1 more source

COLQ-mutation congenital myasthenic syndrome in late adolescence: Case report and review of the literature

Heliyon, 2023
Congenital myasthenia syndromes (CMS) are a heterogeneous group of hereditary disorders of the neuromuscular junction. The symptoms include fatigue, muscle weakness, ptosis, mastication or swallowing problem, respiratory distress.
Yatao Yin, Jing Cao, Yuanteng Fan, Yan Xu   +3 more
doaj   +1 more source

Early onset bilateral juvenile myasthenia gravis masquerading as simple congenital ptosis

GMS Ophthalmology Cases, 2017
Myasthenia gravis is an autoimmune disorder affecting the neuromuscular junction. Ocular myasthenia gravis presents as ptosis with extraocular motility restriction and is prone to be misdiagnosed as third nerve palsy or congenital or aponeurotic ptosis ...
Alam, Md. Shahid, Devi Nivean, Pratheeba
doaj   +1 more source

Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen [PDF]

, 2002
The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus.
Wilcox, Nick, Matthews, I, Stott, David, Ledwidge, S, Vincent, Angela, Willcox, N, Beeson, David, Vincent, A, Sims, G, Stott, D, Matthews, Ian, Sims, Gary, Ledwidge, Serena, Beeson, D   +13 more
core   +1 more source

Long-Term Improvement in a Chinese Cohort of Glucocorticoid-Resistant Childhood-Onset Myasthenia Gravis Patients Treated With Tacrolimus

Frontiers in Neurology, 2022
ObjectivesTo evaluate the long-term outcome of tacrolimus for childhood-onset myasthenia gravis (CMG) with an inadequate response to glucocorticoids, and investigate factors associated with favorable outcomes following tacrolimus treatment.MethodsA ...
Zhuajin Bi, Yayun Cao, Jing Lin, Qing Zhang, Chenchen Liu, Mengcui Gui, Bitao Bu   +6 more
doaj   +1 more source

MYASTHENIA GRAVIS IN CHILDREN AND ADOLESCENTS [PDF]

Acta Medica Iranica, 1994
Myasthenia gravis (MG) is a disorder of the neuromuscular junction. In children, the disease may be congenital or due to an autoimmune process. Clinical manifestations may be purely ocular or may include generalized weakness, fatigability, dysphagia, and
Akbar Soltanzadeh
doaj   +1 more source

Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS [PDF]

, 2012
Myasthenia Gravis (MG) patients suffer from chronic fatigue of skeletal muscles, even after initiation of proper immunosuppressive medication. Since the localization of neuronal nitric oxide synthase (nNOS) at the muscle membrane is important for ...
Meinen, Sarina, Sarina Meinen, Shuo Lin, Lin, Shuo, Rüegg, Markus A., Markus A Rüegg, Punga, Anna Rostedt, Anna Rostedt Punga   +7 more
core   +2 more sources

Pediatric ocular myasthenia gravis: Case report and literature review

The Pan-American Journal of Ophthalmology, 2019
Objective: The objective was to describe a case of ocular myasthenia gravis (MG) in a pediatric patient. Design: This is a descriptive, retrospective study and case report.
Adriana Solano, Veronica Jimeno, Luisa Montoya, Natalia Espinosa   +3 more
doaj   +1 more source