Results 31 to 40 of about 777,243 (151)
Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis
Advanced Science, EarlyView.Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang +9 more
wiley +1 more source
British and Irish Orthoptic Journal, 2012 Aim: To report a case of sudden-onset diplopia, blurred vision and an inability of the left eye to fully abduct following trauma. Subsequent examinations showed significant variability leading to a possible diagnosis of myasthenia gravis. Methods: This
Danielle E. Eckersley +2 more
doaj +1 more source
Early childhood flexibility practices and patterns: report 2014 [PDF]
, 2014 The Early childhood flexibility practices and patterns report highlights recommendations and future directions for early childhood education and care (ECEC) services in providing flexible arrangements for families and local communities.
Early Childhood Australia
core
Constructions of childhood in early childhood education policy debate in New Zealand [PDF]
, 2010 What assumptions about children and childhood are held by government officials and organisation representatives who are influential in policy formation in early childhood education (ECE) in New Zealand? How are assumptions manifested in policy?
Mitchell, Linda, Linda Mitchell
core +1 more source
Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2396-2404, October 2026.ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley +1 more source
Assessment of acute motor deficit in the pediatric emergency room
Jornal de Pediatria (Versão em Português), 2017 Objectives: This review article aimed to present a clinical approach, emphasizing the diagnostic investigation, to children and adolescents who present in the emergency room with acute‐onset muscle weakness.
Marcio Moacyr Vasconcelos +2 more
doaj +1 more source
Muscle &Nerve, Volume 74, Issue 4, Page 1156-1173, October 2026.ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Understanding and evaluating diplopia
Kerala Journal of Ophthalmology, 2019 Diplopia or double vision is a frequent reason for ophthalmology consultation. Monocular diplopia is usually ocular or retinal in origin, whereas binocular diplopia is often due to neurological causes. Detailed history beginning with any childhood visual
Ani Sreedhar, Ashok Menon
doaj +1 more source
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Case report of congenital myasthenic syndrome due to CHRNE mutation diagnosed in adulthood
Northwestern Medical JournalCongenital myasthenic syndromes are a rare subgroup of neuromuscular diseases caused by genetic defects in proteins involved in the structure, function and repair of the neuromuscular junction.
Fatma Bilgili +2 more
doaj +1 more source