Results 61 to 70 of about 829,311 (228)

Multicenter Validation of Machine Learning Models for Predicting Myopia Progression Across School‐Based Screening and Optical Intervention Settings in Chinese Children and Adolescents

Advanced Intelligent Discovery, EarlyView.
Machine‐learning models predict myopia trajectories from 12 routine ocular variables in 40 445 children across 10 hospitals. Externally validated across school‐based screening and optical‐intervention settings, the best models achieve AUROC 0.97 for myopia status and R2 0.83 for spherical equivalent, enabling personalized risk stratification to curb ...
Yitong Zhang, Mingxuan Liu, Yifei Chen, Ying Wu, Lijun Zhang, Mengyao Guo, Yulan Yan, Runmei Wei, Zihan Cui, Peng Luo, Fang Chen, Bo Yang, Youcang Han, Xiaoyang Liu, Qiyuan Tian   +14 more
wiley   +1 more source

Street-view-measured greenspace components and childhood myopia: A population-based cross-sectional and prospective cohort study

Environment International
Background: Greater greenspace exposure may be associated with a lower risk of childhood myopia. However, most studies rely on satellite-derived greenness indices that cannot capture ground-level visual exposure or differentiate greenspace components ...
Yingan Li, Yuzhou Zhang, Charlene C. Yim, Lixian Su, Ka Wai Kam, Poemen Chan, Patrick Ip, Wei Zhang, Alvin Young, Chi Pui Pang, Clement C. Tham, Li Jia Chen, Mei Po Kwan, Jason C. Yam   +13 more
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Effect of Genetic-Environmental Interaction on Chinese Childhood Myopia [PDF]

Journal of Ophthalmology, 2020
Objective. The purpose of this study was to evaluate the effect of genetic-environmental interaction on myopia in Chinese children aged 6 to 9 years. Methods. Students had the physical examination and were required to provide basic demographic information.
Xiyan Zhang, Yan Wang, Chenwei Pan, Wenyi Yang, Yao Xiang, Jie Yang, Fengyun Zhang   +6 more
openaire   +3 more sources

Recurrent Neurodevelopmental Disorder Associated With a Dominant‐Negative TOP2B H63Y Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a 7 year‐old boy with severe neurodevelopmental disorder, medically‐refractory epileptic encephalopathy, hyperkinetic movement disorder, hypotonia, cerebral and cerebellar atrophy and hypomyelination who was found to have a heterozygous de novo TOP2B NM_001330700.2:c.187C>T, p.(His63Tyr) variant.
Zong Yi Ha, Leticia Dinatto, Kirsten Meagher, Colleen Guimond, Jan M. Friedman, Peter C. Stirling, Millan S. Patel   +6 more
wiley   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

The Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

‘I was treated as a deficit’: Immigrant teachers' career progression in Australia

British Educational Research Journal, EarlyView.
Abstract Immigrant teachers have long been recruited through skilled and employer‐sponsored migration schemes to address teacher shortages in Australia, yet their career trajectories remain constrained by systemic inequities that limit their integration and professional development opportunities.
Ching Ting Tany Kwee, Hoa Thi Mai Nguyen, Tony Loughland   +2 more
wiley   +1 more source

Leveraging Double Materiality as a Decision‐Making Tool for ESG Management and Reporting in Hydroponics

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines how the Corporate Sustainability Reporting Directive (CSRD) and double materiality can be integrated within the agri‐food sector, with a particular focus on a company operating in hydroponic agriculture. This study conducts a comprehensive double materiality assessment to evaluate the organization's socio‐environmental ...
Christian Bux, Pasquale Giungato, Serena Sebastiani, Angela Tarabella   +3 more
wiley   +1 more source

Living Through a Revolution: The Coming‐of‐Age of Ethical Anatomy

Clinical Anatomy, EarlyView.
ABSTRACT Ethical issues in anatomy have evolved over many years, driven by a medley of forces both internal and external to anatomy. Since the 1960s the focus of these developments has been on the centrality of informed consent of the donors and/or their families.
David Gareth Jones
wiley   +1 more source