Results 161 to 170 of about 97,617 (258)

Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
Sara El Aouhel   +10 more
wiley   +1 more source

Work Disability, Early Retirement, and Loss of a Loved One in the World Trade Center Health Registry Cohort

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Existing research on the economic outcomes of 9/11 remains limited and has primarily focused on early retirement. Little is known about the prevalence of work disability and loss of a loved one and whether they are associated with survey attrition.
Jennifer Brite   +2 more
wiley   +1 more source

Key protective factors that mitigate the impact of childhood trauma on poor mental health in adulthood: a scoping review protocol. [PDF]

open access: yesBMJ Open
Clarke A   +7 more
europepmc   +1 more source

Implementation of First‐Line Rapid Genome Sequencing for Children in Pediatric and Cardiac Intensive Care Units

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Substantial data supports the use of rapid exome and genome sequencing (rES/rGS) in Neonatal Intensive Care Units (NICU), but fewer studies have examined the impact of rES/rGS in other pediatric critical care units. We evaluated the impact on diagnostic yield and time to diagnosis following a single‐center hospital policy change allowing ...
Alexandra C. Keefe   +22 more
wiley   +1 more source

Gastrointestinal Manifestations in Rubinstein‐Taybi Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Rubinstein–Taybi syndrome is a rare genetic condition associated with a wide range of physical, cognitive, and developmental impairments, yet its gastrointestinal manifestations remain poorly characterized. Case reports and small series suggest a high prevalence of gastroesophageal reflux, constipation, dysphagia, and nutritional compromise ...
Mohamad Abi Nassif   +3 more
wiley   +1 more source

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