Results 41 to 50 of about 12,891 (283)

Frequency and range of childhood traumas amongst women and men.

, 2018
Frequency and range of childhood traumas amongst women and men.
Laura Washington (3939548), Samantha Willan (353656), Nwabisa Shai (3939563), Andrew Gibbs (353654), Kristin Dunkle (315117), Rachel Jewkes (193649)   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Childhood Trauma

The Journal of Humanistic Counseling, Education and Development, 1999
This article describes some of the classic causes of trauma and the symptoms that tend to result when a child has been traumatized, and discusses various considerations that should be made when rendering treatment to children who have been traumatized.
Tony Falasca, Thomas J. Caulfield
openaire   +2 more sources

Childhood trauma in bipolar disorder: experience of Arrazi hospital

European Psychiatry
Introduction Bipolar disorder is a chronic, recurrent, and disabling condition that typically begins in late adolescence or early adulthood. It is characterized by alternating phases of depression, mania, or hypomania.
H. Boukidi, H. Ballouk, M. Sabir, N. Ait bensaid, F. Elomari   +4 more
doaj   +1 more source

Investigation of childhood traumas in inpatient adults with major depression and with or without attention deficit hyperactivity disorder comorbidity (eng)

Klinik Psikiyatri Dergisi, 2020
INTRODUCTION[|]Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood and a significant number of symptoms continue in adulthood.
Esin Erdoğan, Dursun Hakan Delibaş, Emel Pasa Baskin   +2 more
doaj   +1 more source

Mediation role of alexithymia, sensory processing sensitivity and emotional-mental processes between childhood trauma and adult psychopathology: a self-report study

BMC Psychiatry, 2021
Background There is overwhelming evidence for a strong association between childhood trauma and adult psychopathology. This study aimed to investigate the mediation roles of alexithymia, sensory processing sensitivity, and emotional-mental processes in ...
Pelin Karaca Dinç, Seda Oktay, Ayşegül Durak Batıgün   +2 more
doaj   +1 more source

The male nursing students' childhood traumas and attitudes toward violence: A cross-sectional study in Turkey

Archives of Mental Health, 2021
Context: To prevent domestic violence against women, it is critical to identify men's attitudes toward violence itself. Aims: This study aimed to examine the relationship between the experience of childhood trauma and attitudes toward violence in male ...
Sevim Çelik, Ayfer Öztürk, Elif Karahan   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The intermediate role of rumination in the effect of childhood traumas on resilience [PDF]

, 2023
Bu çalışmada çocukluk çağı travmalarının psikolojik sağlamlık üzerindeki etkisinde ruminasyonun aracı rolünün belirlenmesi amaçlanmıştır. Bu doğrultuda çocukluk çağı travmaları, psikolojik sağlamlık ve ruminasyon arasındaki ilişkiler incelenecektir ...
Yeşiltepe, Milayda
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source