Results 61 to 70 of about 12,891 (283)

Psychotic symptoms in young adults exposed to childhood trauma - A 20 year follow-up study

open access: yes, 2011
Childhood adversity has been shown to increase the risk of psychotic symptoms in adult life. However, there are no previous studies looking at the association between experiencing a natural disaster during childhood and the development of psychotic ...
McFarlane, A.   +5 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

Examining the mediator roles of conflict resolution styles and the interpersonal cognitive distortions in the association between childhood trauma and romantic relationship satisfaction

open access: yesKlinik Psikoloji Dergisi
Romantic relationships are at an important point in the lives and interpersonal relationships of individuals. The level of satisfaction they get from their romantic relationships also affects the course of their relationships.
Melisa Minaz
doaj   +1 more source

The relationship between childhood traumas and depression and anxiety in high school students in Turkey

open access: yes, 2017
The aim of this study is to investigate the relationship between childhood traumas and depression and anxiety levels of high school students in Sakarya.
G. Sezer, H. Gulmez, G. Hızlı Sayar
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett   +5 more
wiley   +1 more source

The Effect of Childhood Trauma on Impulsivity in Patients with Bipolar Disorder

open access: yesPsychiatry and Behavioral Sciences, 2019
Objective: This study aimed to examine the association between impulsivity and childhood traumas in bipolar disorder. Materials and Methods: Sixty-four bipolar disorder patients in remission and seventy volunteers were enrolled in this case-control study.
Serhat Tunc, Samet Kose
doaj   +1 more source

AN INTEGRATIVE REVIEW BETWEEN ADVERSE CHILDHOOD EXPERIENCES AND REPRODUCTIVE TRAUMAS

open access: yes, 2022
Adverse childhood experiences, or ACEs, are potentially traumatic events that occur in childhood. Women are more likely to experience multiple ACE events, and ACEs are linked to chronic health problems and pregnancy complications.
Berry, Madison Leigh
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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