Results 41 to 50 of about 384,128 (291)

The Right to Play [PDF]

open access: yes, 2013
This issue of Early Childhood in Focus is published to coincide with the UN Committee on the Rights of the Child's General Comment No. 17 which aims to strengthen implementation of children's right to rest, leisure, play and recreational activities (as ...

core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Closing the Gap Between Rights and Realities for Children and Youth in Urban Brazil: Reflections on a Brazilian Project to Improve Policies for Street Children [PDF]

open access: yes, 2011
Describes the successful use of Children's Rights Councils to promulgate policies to help children who spend their days (and in many cases nights) on the streets.
Irene Rizzini, Malcolm Bush
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Material Rights of Children in Guardianship Maqashid al Sharia Perspective

open access: yesNurani
The material rights of children in the ruling of religious court judges are a very important issue to be studied in relation to the protection of children's rights in guardianship.
Arne Huzaimah, M. Tamudin
doaj   +1 more source

Beyond the new horizon : trends and issues in residential child care [PDF]

open access: yes, 2004
High profile scandals of abuse and poor outcomes of children in residential child care have contributed to a government focus on improving the quality of services.
Kendrick, Andrew
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Lessons for children’s rights from disability rights? [PDF]

open access: yes, 2017
This chapter examines whether the field of children's rights can glean any useful insights from recent developments in the field of disability ...
Sandland, Ralph
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

School Citizenship – Children’s Voices During the Pandemic and the War in Ukraine

open access: yesForum Pedagogiczne
The article concerns school citizenship - children's voices during the pandemic and war in Ukraine. School citizenship is based on viewing children as students able to act in the school environment and entitled to a say in what is done for them and how ...
Anna Górka-Strzałkowska
doaj   +1 more source

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