Results 71 to 80 of about 385,269 (340)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Editorial introduction to special focus: The African Children's Charter at 30: Reflections on its past and future contribution to the rights of children in Africa [PDF]
, 2021 Nkatha Murungi
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Children's rights amidst mkhạṣmạt [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2006 با اذعان به اینکه کودک، به عنوان قشر آسیب پذیر جامعه در زمان بحران و اضطرار نیز رشد و نمو می کند، حمایتهای حقوقی در اسناد بین المللی و عمدتا در دو روند حقوق بشر و حقوق بشر دوستانه، ذکر شده است. این حمایتها بر دو دسته اند: حمایت عام و حمایت خاص، حمایت عام
MOJTABA MOROVAT
doaj
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Playgrounds going wrong: study of the adult style and children's rights during recess in an early childhood and primary education center [PDF]
, 2016 Recent perspectives on Pedagogy for Early Childhood Education emphasize children's participation in line with the Children's Rights Convention. The study aimed to analyse how children's rights are dealt with during recess in a school (Early Childhood ...
Figueiredo, Maria Pacheco +1 more
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Demonstrating Positive Obligations: Children's Rights and Peaceful Protest in International Law [PDF]
, 2013 Recently there has been a significant increase in the involvement of children and young people in protests across the globe. As a result of this increase, children have directly influenced political change but have also faced threats to their safety ...
Daly, Aoife
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Child labor, education, and children's rights [PDF]
Child labor is widespread, and bad for development, both that of the individual child, and of the society and economy in which she, or he lives. If allowed to persist to the current extent,child labor will prevent the achievement of the Millennium ...
Betcherman, Gordon +3 more
core