Results 71 to 80 of about 925,473 (318)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Can Asset Mapping be Used to Gain Insight into Children's Wellbeing [PDF]
, 2012 In recent years, there has been an enormous growth in the literature that has focussed upon assets, in other words emphasising the positive attributes of both people and communities; these include children and young people’s developmental assets ...
Whiting, Lisa Suzanne
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Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Boys and girls come out to play: Gender differences in children\u27s play patterns [PDF]
, 2017 This paper presents findings from The Irish Neighbourhood Play Study; a national, cross-border research project which recorded children’s play patterns in Ireland during 2012. The study incorporated 1688 families across 240 communities.
McCormack, M +3 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Investigating the home literacy environment and emergent literacy skills of children as they start school in New Zealand : a thesis in partial fulfilment of the requirements for the degree of Master of Educational Psychology, Massey University, Albany, New Zealand [PDF]
, 2017 Home literacy environment (HLE) has been consistently linked with children’s early literacy skills in international research, and is argued to be an important variable influencing the development of children’s emergent literacy.
Van Tonder, Brittney Elizabeth
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Black Girls, White Girls, American Girls: Slavery and Racialized Perspectives in Abolitionist and Neoabolitionist Children’s Literature [PDF]
, 2017 Analyzing abolitionist and neoabolitionist girlhood stories of racial pairing from the nineteenth and twenty-first centuries, this essay shows how children’s literature about interracial friendship represents differently racialized experiences of and ...
Brigitte Fielder
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Postmodernism and Children’s Literature
, 2007 All four of my own children clamored for the Sesame Street book titled, The Monster at the End of This Book. On each double page spread, Grover begged them, “Please don’t turn the page because there’s a monster at the end of this book and I am so scared ...
Atken, Adel
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