Results 61 to 70 of about 69,428 (233)

A Comparative Reading of Children's Economic Rights in the Legal Systems of Iran, the United States, and International Instruments [PDF]

open access: yesپژوهش‌نامه حقوق اسلامی
‌‌Context & Objective: Children's economic rights are a critical dimension of human rights, requiring focused legal protection across various jurisdictions and international frameworks. This article explores and compares the legislative approaches toward
Mahdi Mollaei
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane   +19 more
wiley   +1 more source

Children's Rights Awareness as a Predictor of Social Reasoning Among Primary School Pupils

open access: yesProfesi Pendidikan Dasar
Children's rights awareness may contribute to social and interpersonal development, yet empirical evidence on its relationship with social reasoning among primary school pupils remains limited in Nigeria.
Ibrahim Yakub Karatu   +3 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Children’s Wellbeing and Children’s Rights—A Nordic Perspective

open access: yesSocial Sciences
Children’s rights and wellbeing have increasingly attracted attention both politically and in the scholarly field [...]
Sarah Alminde, Hanne Warming
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

Caregivers' views on the risk factors impeding implementation of provision rights in children's homes in Harare, Zimbabwe

open access: yesSocial Sciences and Humanities Open
This article focuses on caregivers' views on the risk factors impeding the implementation of children's provision rights in the early childhood development phase in seven children's homes in Harare, Zimbabwe.
Blessing Tendai Baloyi   +2 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

INTERNATIONAL LEGAL MECHANISM FOR PROTECTING CHILDREN’S ENVIRONMENTAL RIGHTS AT THE INTERNATIONAL UNIVERSAL LEVEL

open access: yesВісник Харківського національного університету імені В. Н. Каразіна Серія: «Право»
Introduction. The article examines the peculiarities of the formation and functioning of the international legal mechanism for protecting children’s environmental rights at the international universal level within the framework of the United Nations. The
Ihor Voievodin
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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