Results 81 to 90 of about 540,140 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Caregivers' views on the risk factors impeding implementation of provision rights in children's homes in Harare, Zimbabwe

Social Sciences and Humanities Open
This article focuses on caregivers' views on the risk factors impeding the implementation of children's provision rights in the early childhood development phase in seven children's homes in Harare, Zimbabwe.
Blessing Tendai Baloyi, Jace Pillay, Lucia Munongi   +2 more
doaj   +1 more source

A bully in the playground : examining the role of neoliberal economic globalisation in children’s struggle to become ‘fully human’ [PDF]

, 2010
This article begins by exploring the Western historical progression of the conceptual place of children along a Property-Welfare-Rights continuum. It applies Baxi’s “logics of exclusion and inclusion” to the complex dynamic of children’s advancement in ...
Davidson, Jennifer
core  

Students' Perceptions of their Rights in Portugal [PDF]

, 2001
The present study analyses young Portuguese students’perceptions of their rights at school and at home. The sample consisted of 294 male and female students, in Year 7 to Year 9, from several regions in the country.
Veiga, Feliciano Henriques
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Children’s Wellbeing and Children’s Rights—A Nordic Perspective

Social Sciences
Children’s rights and wellbeing have increasingly attracted attention both politically and in the scholarly field [...]
Sarah Alminde, Hanne Warming
doaj   +1 more source

To Their Fullest Potential? Conceptualising the Adequacy of Children's Living Standards for their Development [PDF]

, 2013
This author accepted manuscript (post print) is made available in accordance with publisher copyright policyIn this paper a framework is proposed for conceptualising ‘fullest potential’ towards which, according to the Convention on the Rights of the ...
Redmond, Gerry
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Children’s rights online: challenges, dilemmas and emerging directions [PDF]

, 2014
In debates over internet governance, the interests of children figure unevenly, and only partial progress has been made in supporting children’s rights online globally.
A Giddens, A Millwood Hargrave, A Powell, A Thierer, B O’Neill, B O’Neill, B Shmueli, C Nesson, CB Preston, CJ Hamelink, CT Marsden, D Archard, D Flint, D Muir, D Oswell, D Tambini, Deloitte and European Commission, E Bartholet, E Helsper, E Quale, F Olsen, GSMA, H Holzscheiter, I Schoon, J Griffin, J Lembke, J McNamee, J Palfrey, J Rosen, J Zittrain, K Ala-Mutka, L Criddle, L Green, L Lessig, LM Jones, LM Purdy, LS Clark, M Foley, M Freeman, M Guggenheim, M Warschauer, Nordic Youth Forum, O O’Neill, OECD, P Alderson, P Anthonysamy, P Lunt, P Pruulmann-Vengerfeldt, PE Veerman, R Mansell, S Livingstone, S Livingstone, S Livingstone, S Livingstone, S Livingstone, S Livingstone, S Livingstone, S McLaughlin, U Gasser, V Mayer-Schönberger, W Lusoli, W Schulz, W Webster, WH Dutton   +63 more
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source