Results 231 to 240 of about 9,035,003 (377)
AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun+10 more
wiley +1 more source
A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang+6 more
wiley +1 more source
Actor-Partner Model of Parenting and Co-Parenting Practices and Youth Resilience During the COVID-19 Pandemic. [PDF]
Aspiras O, O'Gara J, Radunzel J.
europepmc +1 more source
A Preliminary Note on an Epidemic of Paralysis in Children: (One Hundred and Twenty Cases) [PDF]
A. Macphail
openalex +1 more source
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai+14 more
wiley +1 more source
Disparity in school children's reading skills in 11 African countries. [PDF]
Zhang H, Holden ST.
europepmc +1 more source
THE BACTERIOLOGY OF ACUTE RESPIRATORY INFECTIONS IN CHILDREN AS DETERMINED BY CULTURES FROM THE BRONCHIAL SECRETION [PDF]
L. Emmett Holt
openalex +1 more source
Independent Final Evaluation of Combating Child Labor and Exploitation through Education in Guinea (CCLEE). [PDF]
Save the Children
core +1 more source