Results 31 to 40 of about 10,106,490 (366)
Background Effective measurement of Gender Equality and Women’s Empowerment (GEWE) is challenging in low and middle-income countries (LMICs), and even more so in humanitarian settings.
Céline M. Goulart+6 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Introduction The cultural revolution of data sharing is becoming a global movement. It allows for scientific replication and verification of research results, avoiding research duplication, and enabling greater transparency and knowledge mobilization ...
Yunqi Zhang+5 more
doaj +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
The Economic Crisis and the Health, Well-Being and Security of New York's Children and Families: Report of a Meeting, March 13, 2009 [PDF]
The March 2009 New York Child Health Forum shed light on troubling long-term trends that have become only more salient in the context of today's economic crisis.
National Center for Children in Poverty
core +2 more sources