Results 101 to 110 of about 557,494 (317)

Kick Scooter Injuries in Children and Adolescents : Minor Fractures and Bruise [PDF]

, 2018
Background: Kick scooters are popular among children in both transportation and recreational activities. The aim of this retrospective study was to assess the incidence of and injury patterns associated with kick scooter accidents in school-aged children
Kallio, P., J. H. Unkuri, S. Kosola, Unkuri, J. H., Kosola, S., Salminen, P., P. Kallio, P. Salminen   +7 more
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Progressive Liver Disease in Patients With Ataxia Telangiectasia

Frontiers in Pediatrics, 2019
Ataxia telangiectasia (A-T) is a devastating multi-system disorder characterized by progressive cerebellar ataxia, immunodeficiency, genetic instability, premature aging and growth retardation.
Helena Donath, Sandra Woelke, Marius Theis, Ursula Heß, Viola Knop, Eva Herrmann, Dorothea Krauskopf, Matthias Kieslich, Ralf Schubert, Stefan Zielen   +9 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

In vitro study of TSC1 deficiency in preadipocytes: insights into development and treatment options for tuberous sclerosis related lipomatosis

Orphanet Journal of Rare Diseases
Background Tuberous sclerosis complex (TSC) is a rare genetic neurocutaneous disorder resulting from mutations in the TSC1 or TSC2 genes, characterized by overgrowth and lesions in multiple organs.
Julika E. Friedrich, Julia Hentschel, Sandy Richter, Henriette Kiep, Maria Arélin, Konrad Platzer, Torsten Schulz, Andreas Merkenschlager, Wieland Kiess, Steffi Mayer, Rami Abou Jamra, Diana Le Duc, Antje Garten, Anna S. Kirstein   +13 more
doaj   +1 more source

ESTIMATING CALORIC EXPENDITURE USING THE PHYSICAL ACTIVITY INDEX (PAI) IN CHILDREN AND ADOLESCENTS PERFORMING A MULTISTAGE MAXIMAL EXERCISE TEST [PDF]

, 2014
PURPOSE: The primary purposes of this investigation were (a) to examine the validity of the PAI, (b) to develop a statistical model to predict cumulative Kcal expenditure using PAI as the predictor variable and (c) to develop a statistical model to ...
Gairola, Anjuli
core  

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Deliberate Self Harm in Children and Adolescents

This study compared children and adolescents who had deliberately selfharmed (DSH) with those who had not using data routinely collected during assessment at a Child and Adolescent Mental Health Service (CAMHS). The DSH group consisted of 64 boys and 194
McCarthy-Hoffbauer, Iris, McKenzie, Immanuel, Leach, Chris   +2 more
core   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham, Thea Senger‐Carpenter, Jocelyn Zuckerman, Michelle Adler, Mallet R. Reid, Ashley Danguecan, Luana Flores Pereira, Sarah I. Mossad, Samantha L. Ely, Khalid Abulaban, Elizabeth A. Kessler, Natalie Rosenwasser, Tamar B. Rubinstein, Ekemini A. Ogbu, Emily A. Smitherman, Alaina Miller, Taylor Abounader, Elizabeth Ross, Livie Timmerman, Dhriti Sharma, Jennifer N. Stinson, Stacy Allen, Kabita Nanda, Tala El Tal, Deborah M. Levy, Linda T. Hiraki, Hermine I. Brunner, Mathew Reeves, Steven J. Pierce, Andrea Knight   +29 more
wiley   +1 more source

The state of physical and mental health of children from the anti-terrorist operation zone

Zdorovʹe Rebenka, 2017
The aim of the study was the assessment of physical and mental health of school-age children from the war zone in the Eastern Ukraine. Materials and methods.
N.M. Korenev, I.S. Lebets, S.R. Tolmachova, V.V. Nikonova, Т.Yu. Proskurina, Т.N. Matkovska   +5 more
doaj   +1 more source