Results 41 to 50 of about 1,079,925 (266)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2017 The history of children in care in the United Kingdom is long and fractured. Peter Higginbotham's work Children's Homes: A History of Institutional Care for Britain's Young is an attempt to look at the history of children's establishments and the ...
Ben Quail
doaj +1 more source
International Journal of Adolescence and Youth, 2020 Children in care (CiC) experience poorer health outcomes than their same-aged peers without an experience of care. Despite growing recognition of the importance of listening to the voices of children and young people (YP), to date, the voices of CiC are ...
Madelaine Smales +5 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2009 This book details research which aimed to identify the ways in which the managers of effective residential homes work. The research involved the collection of quantitative data from 45 homes in England and Wales, 30 homes from the local authority and 15 ...
Graham McPheat
doaj +1 more source
Book review: Labours of Love: The Crisis of Care by Madeleine Bunting
Scottish Journal of Residential Child Care, 2021 Journalist and broadcaster Madeleine Bunting spent five years researching what she calls a 'quiet crisis buried in individual lives' (p.5). The book's page proofs arrived with the author just after the UK had gone into lockdown because of the COVID-19 ...
Graham Connelly
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2009 As a result of the continuing high levels of disadvantage, social exclusion and poor outcomes experienced by children and young people who are looked after and accommodated in the UK, the authors of this book undertook studies of residential care ...
Margaret-Anne Haggarty
doaj +1 more source