Results 81 to 90 of about 1,112,929 (217)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Scottish Journal of Residential Child Care, 2014 The Panopticon by Edinburgh poet and writer Jenni Fagan is not for the faint hearted. It is a novel about a 15-year-old girl named Anais who is living in a residential care home on the outskirts of a large Scottish city, and Jenni Fagan has been very ...
Autumn Roesch-Marsh
doaj +1 more source
Nursing staff involvement of children in care activities: A cross-sectional study. [PDF]
Int J Nurs Stud Adv, 2023 Bawah RK +5 more
europepmc +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2014 For young people in care the pathway through education can be littered with obstacles. Traumatic experiences sustained prior to (or as a result of) coming into care are often compounded by placement instability, school disruption and inadequate support ...
Ben Farrugia
doaj +1 more source
Immunisation status of children receiving care and support in Wales: a national data linkage study. [PDF]
Front Public Health, 2023 Bailey GA +6 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
Helping children in care cope with loss and change: nature's way
Scottish Journal of Residential Child Care, 2015 One of my closest friends is a foster carer who has just become the mother of a newly adopted child. I have watched her expertly bring up her own children and then spent many hours with her talking through the pros and cons of becoming a foster carer. It
Caroline Jay
doaj +1 more source
Gender, Addiction, and Removal of Children Into Care. [PDF]
Front Psychiatry, 2022 Russell L +3 more
europepmc +1 more source