Results 31 to 40 of about 1,947,105 (313)

OT 060420: A Seemingly Optical Transient Recorded by All-Sky Cameras [PDF]

open access: yes, 2006
We report on a ~5th magnitude flash detected for approximately 10 minutes by two CONCAM all-sky cameras located in Cerro Pachon - Chile and La Palma - Spain. A third all-sky camera, located in Cerro Paranal - Chile did not detect the flash, and therefore
Arter T. R.   +11 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Las Maestras Parvularias a Inicios del Siglo XX en Chile [PDF]

open access: yesCabás, 2014
El artículo nos describe la evolución de la enseñanza parvularia en Chile. Podemos ver cómo ya en el periodo precolombino existía una atención en los primeros años del niño.
Muñoz, E. S.
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A contribution to the Campylopus flora of Chile [PDF]

open access: yes, 2005
A key to the species of Campylopus known from Chile is given, completed by records of Campylopodioideae of the author in southern Chile. Campylopus acuminatus Mitt. var. kirkii (Mitt.) J.-P.
Frahm, Jan-Peter
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Historias Naturales, expediciones, redes globales y Museos de Historia Natural en Chile (siglos XVIII-XIX)

open access: yesRevista de Historiografía, 2023
Los museos de Historia Natural en Chile han sido objeto creciente de interés histórico al tratarse de instituciones estrechamente vinculadas a la formación del estado-nación y protagonistas de la configuración de una cultura científica en el país. En las
Carolina Valenzuela Matus   +1 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Neoliberalizmin Gölgesinde Toplumsal Cinsiyet Eşitsizliği ile Mücadele: Şili Analizi

open access: yesLectio Socialis, 2021
Temel olarak refahın arttırılmasını misyon edinen politik ekonomik teori neoliberalizm, bireysel özgürlüklerin güvence altına alınmasını ve serbest piyasa ekonomisinin dış müdahalelerden olabildiğince arındırılmasını zorunlu kılmaktadır.
Gökhan Çi̇n
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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