Results 141 to 150 of about 6,753,342 (308)
Advanced Science, EarlyView.Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang +5 more
wiley +1 more source
ANÁLISIS DE UN TEXTO DE ARGUMENTACIÓN CIENTÍFICO ESCOLAR: DE LOS ESTUDIANTES AL PROFESOR
Bio-grafía, 2014 El objetivo del estudio fue explorar los atributos de un texto argumentativo producido por estudiantes y la representación sobre ello de 8 profesores de biología noveles.
Eduardo Ravanal Moreno +3 more
doaj
Advanced Science, EarlyView.During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang +8 more
wiley +1 more source
Evaluating the Chile Solidario program: results using the Chile Solidario panel and the administrative databases [PDF]
This paper presents the results of a three-year evaluation performed on the first cohorts of Chile Solidario, the most important anti-poverty program in Chile.
Andrés Hojman +2 more
core
Advanced Science, EarlyView.Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin +10 more
wiley +1 more source
Climatic potential for viticulture in Central Chile [PDF]
Australian Journal of Grape and Wine Research, 2011 C. MONTES +3 more
openaire +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Advanced Science, EarlyView.Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao +5 more
wiley +1 more source
Central's first homecoming; male students standing on street in single file line
, 1920 In Central Methodist University (formerly Central College)'s first homecoming parade, male students in costume stand in single file on an unpaved road in Fayette ...
Central Methodist University, Smiley Memorial Library
core +1 more source
Advanced Science, EarlyView.HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun +12 more
wiley +1 more source