Results 161 to 170 of about 940,909 (306)

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou   +10 more
wiley   +1 more source

Separating tectonic and climate signals in Holocene sea-level records using marine terraces in central Chile. [PDF]

open access: yesSci Rep
Melnick D   +5 more
europepmc   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

open access: yesAdvanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan   +13 more
wiley   +1 more source

Rentabilidad de la educación en microemprendedores: Los retornos por nivel educativo en la región de Valparaíso, Chile

open access: yesIngeniare: Revista Chilena de Ingeniería
La educación y el emprendimiento son considerados motores fundamentales para el desarrollo de una sociedad. El presente estudio tiene como propósito realizar un análisis de la rentabilidad de la educación en el sector emprendedor.
Valeria Scapini Sánchez   +2 more
doaj  

Correction: Performance of a national primary care chronic disease screening strategy in Chile: a mixed-methods analysis. [PDF]

open access: yesBMC Health Serv Res
Zamorano P   +6 more
europepmc   +1 more source

Reconstructed Polyamide Nanolayers via Two‐Stage Interfacial Polymerization Engineering for Precise Ion Sieving

open access: yesAdvanced Science, EarlyView.
A reconstructed polyamide nanofiltration membrane is engineered via a two‐stage interfacial polymerization strategy for lithium extraction from complex brines. Incorporated bidentate quaternary ammonium monomers enable synergistic steric and electrostatic effects within sub‐nanometer channels, achieving 60‐fold lithium enrichment and demonstrating ...
Shuzhen Zhao   +9 more
wiley   +1 more source

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