Results 11 to 20 of about 99,332 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Coastal erosion in central Chile: A new hazard?

Ocean & Coastal Management, 2018
Abstract The coasts of central Chile are increasingly affected by human activity. To date, there are no clear symptoms of shoreline change in the area; however, the incidence of recent extreme storms, in conjunction with an increase in urban area, may have created a new coastal hazard in addition to earthquakes and tsunamis.
Martínez Reyes, Carolina del Pilar, Contreras-Lopez, Manuel, Winckler, Patricio, Hidalgo, Hector, Godoy, Eduardo, Agredano, Roberto   +5 more
openaire   +4 more sources

COLLECTION OF FRAGARIA IN CENTRAL AND SOUTHERN CHILE [PDF]

HortScience, 1990
In January, 1990, a team of U.S. and Chilean scientists collected native and cultivated Fragaria from central and southern Chile. During the course of this expedition, 363 new accessions of Fragaria were collected.
Thomas M. Sjulin, J. Scott Cameron, Carl H. Shanks, Carlos E. Munoz   +3 more
openaire   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Vulnerabilidad territorial y capacidad institucional en el litoral central de Chile

, 2023
El GEOlibro “Hacia una Ley de Costas en Chile: bases para una Gestión integrada de Áreas Litorales” es un esfuerzo académico del Instituto de Geografía de la Pontificia Universidad Católica de Chile, el Proyecto Fondecyt No 1200306; de la Cátedra UNESCO ...
Hernández Farías, Pilar Andrea, Vicuña del Río, María Magdalena, Vecchio, Giovanni, Vega Zurita, Patricio Esteban, Martínez Reyes, Carolina del Pilar, Moris Iturrieta, Roberto, Bastías Acuña, Gabriela   +6 more
core  

Selenium Concentration in Compartments of Aquatic Ecosystems in Central Chile

Bulletin of Environmental Contamination and Toxicology, 2002
69
Pinochet, H, De Gregori, I, Cavieres, MF
openaire   +4 more sources