Results 191 to 200 of about 5,077,095 (347)

Agregados Monetarios: Nuevas Definiciones [PDF]

Central bankers have devoted considerable efforts to monitoring and analyzing the various measures of money. In Chile, the definitions of monetary aggregates—barring a few minor changes—have been in place since the 1980s and range from M1 to M7, a ...
Erika Arraño G.
core  

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

Ocean Chlorophyll-a Concentration and the Extension of the Migration of Franklin's Gulls (Leucophaeus pipixcan) in Southern South America. [PDF]

Animals (Basel)
Acuña-Ruz MP, Quintero-Galvis JF, Vukasovic AM, Hodge J, Estades CF.   +4 more
europepmc   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

Advanced Science, EarlyView.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo, Yilei Guo, Yanrong Zhu, Ke Yan, Yulai Fang, Jiafeng Zhang, Yue He, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Correction: Padel related injuries: prevalence and characteristics in Chilean amateur players - a cross sectional analytic study. [PDF]

BMC Sports Sci Med Rehabil
Belmar-Arriagada H, Gajardo-Burgos R, Armstrong R, Bascour-Sandoval C.   +3 more
europepmc   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Rentabilidad de la educación en microemprendedores: Los retornos por nivel educativo en la región de Valparaíso, Chile

Ingeniare: Revista Chilena de Ingeniería
La educación y el emprendimiento son considerados motores fundamentales para el desarrollo de una sociedad. El presente estudio tiene como propósito realizar un análisis de la rentabilidad de la educación en el sector emprendedor.
Valeria Scapini Sánchez, Pedro Gallardo Flores, Skander López Galbán   +2 more
doaj  

ADIVINANZAS DE CHILE CENTRAL

Sociedade e Cultura, 2007
openaire   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

Composition of Necrophagous Insect Assemblages in Altitudinal Gradient of Central Chile. [PDF]

Insects
Marzolo Bown M, Thyssen PJ, Marrara Prado A, Villagra C.   +3 more
europepmc   +1 more source