We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang +10 more
wiley +1 more source
Phytophthora capsici carries and differentially expresses genes for the RNA interference pathway. [PDF]
Sevillano-Serrano J +5 more
europepmc +1 more source
Gates Chili Central School District and Gates Chili Transportation Union (2003) [PDF]
core +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Comparative study on flavor metabolites in different components of dried chili and fermented chili: whole chili, chili pericarp and chili seed. [PDF]
Chen L, Mu Y, Su W, Jiao Y, Li L, Luo H.
europepmc +1 more source
Churchville-Chili Central School District and Churchville-Chili Bus Drivers Association (2001) [PDF]
core +1 more source
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue +17 more
wiley +1 more source
Decoding heavy metals (Cd<sup>2</sup>⁺ and Cr⁶⁺) / metalloid (As<sup>3</sup>⁺) toxicity: unmasking physiological, biochemical and genotoxic consequences in green chili. [PDF]
Shahid M +5 more
europepmc +1 more source
Stress‐Induced Melting Controlled Failure Mechanisms of Methane Hydrate
We study methane hydrate via nanoindentation and nuclear magnetic resonance (NMR), finding its regional melting and mechanical properties, challenging existing views on hydrogen‐bonded crystals. Abstract Methane hydrate, a kind of nonstoichiometric crystalline, attracted worldwide attentions as a promising substitute energy. Its Dissociation is thought
Yanlong Li +9 more
wiley +1 more source

