Results 21 to 30 of about 13,626 (219)

Apport des modèles mathématiques et big data pour la prise de décisions de l'entreprise; le cas d'épidémies telles que le SARS-CoV-2 dans le secteur de la santé au Chili

open access: yesRevue Internationale des Économistes de Langue Française
La pandémie causée par le virus COVID-19 a fait l'objet de nombreuses analyses et études en raison de ses incidences et conséquences graves dans tous les secteurs du développement humain au niveau mondial.
Alexis Matheu, Paola Juica
doaj   +1 more source

Por qué la neurociencia debería ser parte de la formación inicial docente? [PDF]

open access: yesSynergies Chili, 2019
Existe un marcado interés de parte de los profesores por adquirir conocimientos en neurociencia, e incluso a menudo se exalta la relevancia de esta disciplina para la educación.
Roberto Ferreira Campos   +1 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Les barrages et leurs promoteurs. Pour un discours de la technique dans la controverse d’HidroAysén [PDF]

open access: yesSynergies Chili, 2017
L’article propose une analyse concernant la construction médiatique d’un conflit socio-environnemental dans la Patagonie chilienne (projet HidroAysén). La médiatisation du consensus technique, économique et politique autour du projet est l’objet de notre
Claudio Broitman, René Jara
doaj  

Primary Students’ Argumentation on Factors Affecting Dissolving

open access: yesScience Education International, 2018
The study explored the possibilities to improve students’ argumentation ability concerning factors that affect dissolving, through the implementation of two versions of a teaching scheme, with and without particle theory.
Anastasia Angeloudi   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

La construction discursive de l’événement conflit mapuche dans la presse écrite chilienne [PDF]

open access: yesSynergies Chili, 2016
Ce travail analyse la construction discursive autour de l’événement conflit mapuche dans deux quotidiens chiliens dans le cadre d’une perspective française de l’analyse du discours.
Pablo Segovia Lacoste
doaj  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Guiding chili variety selection for Zao chili in Guizhou: Based on a systematic study of sensory, physicochemical, and volatile characteristics

open access: yesFood Chemistry: X
This work investigated the influence of seven chili varieties in Guizhou on the quality of Zao Chili (ZC), a local traditional fermented chili product.
Xueya Wang   +7 more
doaj   +1 more source

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