Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Combining temperate fruit tree cultivars to fit spring phenology models. [PDF]
Caspersen L +3 more
europepmc +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Impact of warmer winters on the flowering display of Tokyo cherry (Cerasus ×yedoensis 'Somei-yoshino') at its southern range. [PDF]
Katsuki T +6 more
europepmc +1 more source
Direct aluminium-alloy upcycling from entire end-of life vehicles. [PDF]
Krall P +8 more
europepmc +2 more sources
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
R-based workflow to estimate chilling requirements in multiple fruit tree genotypes using Partial Least Squares regression: <i>Prunus armeniaca</i> L. case. [PDF]
Muñoz-Morales AM +6 more
europepmc +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Raspberries and blackberries: establishment and management
Raspberries require well drained, deep soil. They do not tolerate heavy clay soils, or shallow soils, or prolonged water stress. They can tolerate heat in summer, but hot wind will devastate new growth and economic viability.
Department of Environment and Primary Industries
core
Modeling Phenological Phases across Olive Cultivars in the Mediterranean. [PDF]
Didevarasl A +10 more
europepmc +1 more source

