Results 151 to 160 of about 7,776 (287)

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Рене Декарт и Ars chimaera

, 2010
Подорога Валерий Александрович. Рене Декарт и Ars chimaera [Электронный ресурс] / В. А. Подорога// Культура и форма : к 60-летию А. Л. Доброхотова : сб. науч. тр. / Гос. ун-т Высш. шк. экономики. - М. : ГУ ВШЭ, 2010. - С.
Подорога Валерий Александрович
core  

Novel Hawai'i and Pacific Island circulating clusters of <i>Mycobacterium intracellulare</i> subsp. <i>chimaera</i>. [PDF]

Appl Environ Microbiol
Wilsey RN, Ding L-H, Dawrs SN, Raulerson CK, Norton GJ, Virdi R, Hasan NA, Epperson LE, Nelson ST, Holst B, Chan YL, Kitamura K, Awaya JD, Irwin SV, Cornell S, Cannon MB, Anglin S, Chelius MK, Hutchinson R, Kern S, Stearns A, Strong M, Chan ED, Crooks JL, Honda JR.   +24 more
europepmc   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Lungs and Beyond: Seizures as Presenting Symptom in a Patient With <i>Mycobacterium chimaera</i> Infection. [PDF]

J Community Hosp Intern Med Perspect
Mehyar S, Adhikari T, Kambali S, Ghumman HK, Ghumman AK, Sud P, Sabet MF, Mikhail E, Singh S.   +8 more
europepmc   +1 more source

Aggregation chimaeras [PDF]

Nature, 1977
openaire   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Genetic diversity and phylogeography of Chimaera monstrosa (Linnaeus, 1758) in the Mediterranean Sea: insights from COI mitochondrial DNA analysis. [PDF]

Sci Rep
Başusta N, Saglam N.
europepmc   +1 more source

Chimaera

Todas as Letras: Revista de Língua e Literatura, 2016
openaire   +1 more source

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source