The <i>Mycobacterium avium</i> Complex: Genomics, Disease, and Beyond. [PDF]
Matos S, Portugal I, Perdigão J.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Delayed diagnosis of disseminated <i>Mycobacterium intracellulare</i> subsp. <i>chimaera</i> infective endocarditis via cell-free metagenomic next-generation sequencing: a case report. [PDF]
Ladines-Lim JB +12 more
europepmc +1 more source
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
Rapid clinical detection of mycobacterial infections using M-Typer and flow-injection tandem mass spectrometry. [PDF]
Głogowska A +4 more
europepmc +1 more source
Sensing and Reprogramming Surface Receptor Activation With Synthetic Transcriptional Circuits
A synthetic receptor‐signalling induced transcription (RESIT) circuit is designed based on receptor activation mediated split protease complementation and release of membrane‐tethered synthetic transcriptional modules. The RESIT system enables probing Ca2+ entry, receptor tyrosine kinase (RTK) activities and Ras activation, and reprogramming RTK ...
Fei Liu +5 more
wiley +1 more source
Heterogeneity among <i>Mycobacterium avium</i> complex species isolated from pulmonary infection in Taiwan. [PDF]
Lin H-M +16 more
europepmc +1 more source
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu +10 more
wiley +1 more source
Comparative evaluation of molecular technologies for the identification of prevalent non-tuberculous mycobacteria in pulmonary infections: a systematic review and meta-analysis. [PDF]
Chen X +5 more
europepmc +1 more source

