Results 211 to 220 of about 10,407 (325)

Delayed diagnosis of disseminated <i>Mycobacterium intracellulare</i> subsp. <i>chimaera</i> infective endocarditis via cell-free metagenomic next-generation sequencing: a case report. [PDF]

ASM Case Rep
Ladines-Lim JB, Yang WT, Tebas P, O'Donnell J, Koenig H, Kreider E, Dyer K, Anwar M, Rodriguez E, Patel S, Rodino K, Glaser L, Richterman A.   +12 more
europepmc   +1 more source

The Chimaera of Arezzo [PDF]

American Journal of Archaeology, 2010
openaire   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Heterogeneity among <i>Mycobacterium avium</i> complex species isolated from pulmonary infection in Taiwan. [PDF]

Microbiol Spectr
Lin H-M, Shu C-C, Chen C-H, Chen N-Y, Yang J-H, Chen C-H, Li S-H, Wang C-L, Yu C-T, Lin S-M, Kao K-C, Huang C-C, Yang C-T, Lu J-J, Chiu C-H, Lai H-C, Wu T-S.   +16 more
europepmc   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Rapid clinical detection of mycobacterial infections using M-Typer and flow-injection tandem mass spectrometry. [PDF]

IJTLD Open
Głogowska A, Majewski K, Szulc B, Kowalski K, Augustynowicz-Kopeć E.   +4 more
europepmc   +1 more source

Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects

Advanced Science, EarlyView.
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu, Ke Wang, Kaizhong Lu, Tianlun Hou, Yuan Chen, Xian Wang, Hongchuan Jin   +6 more
wiley   +1 more source

Comparative evaluation of molecular technologies for the identification of prevalent non-tuberculous mycobacteria in pulmonary infections: a systematic review and meta-analysis. [PDF]

Ann Med
Chen X, Sun J, Chen X, You Y, Sechi LA, Molicotti P.   +5 more
europepmc   +1 more source

Plant Chimaeras [PDF]

Nature, 1969
openaire   +1 more source

Synergistic Remodeling of Tumor Immune Microenvironment via a DNA Nanodevice Integrating STING Activation and Lysosome‐Targeted PD‐L1 Degradation

Advanced Science, EarlyView.
A rational design DNA nanoplatform not only achieves efficient PD‐L1 degradation but also triggers robust STING signaling. The nanodevice effectively reprograms “cold” tumors, leading to potent inhibition of tumor growth and metastasis in vivo. ABSTRACT The cGAS‐STING pathway is a cornerstone of innate antitumor immunity; however, its therapeutic ...
Haoxiang Li, Min Hou, Shasha Sun, Jun Cao, Jian‐Hui Jiang, Jianjun He   +5 more
wiley   +1 more source