Results 221 to 230 of about 7,776 (287)

Moving north: Warmer waters expand populations of deep-water cartilaginous fishes into Arctic waters. [PDF]

PLoS One
Jac R, Albretsen J, Höffle H, Lennox RJ, Staby A, Zimmermann F, Junge C.   +6 more
europepmc   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

Advanced Science, EarlyView.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li, Junting Guan, Yifan Song, Hongxia Yang, Guangtao Li, Xiaodong Zhao, Jiaxin Liu, Bin Liu, Yang Tan, Honglan Zhou, Yang‐He Zhang, Yishu Wang   +11 more
wiley   +1 more source

Heterogeneity among <i>Mycobacterium avium</i> complex species isolated from pulmonary infection in Taiwan. [PDF]

Microbiol Spectr
Lin H-M, Shu C-C, Chen C-H, Chen N-Y, Yang J-H, Chen C-H, Li S-H, Wang C-L, Yu C-T, Lin S-M, Kao K-C, Huang C-C, Yang C-T, Lu J-J, Chiu C-H, Lai H-C, Wu T-S.   +16 more
europepmc   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Rapid clinical detection of mycobacterial infections using M-Typer and flow-injection tandem mass spectrometry. [PDF]

IJTLD Open
Głogowska A, Majewski K, Szulc B, Kowalski K, Augustynowicz-Kopeć E.   +4 more
europepmc   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Consequences of Climate Change on the Emergence of Pathogenic, Environmentally Acquired Nontuberculous Mycobacteria. [PDF]

Open Forum Infect Dis
Koch TN, Banta JA, Wilsey RN, Chan ED, Crooks JL, Honda JR.   +5 more
europepmc   +1 more source