Results 61 to 70 of about 10,407 (325)

Mycobacterium intracellulare subsp. chimaera from Cardio Surgery Heating-Cooling Units and from Clinical Samples in Israel Are Genetically Unrelated

Pathogens, 2021
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens that cause illness primarily in the elderly, in the immunocompromised or in patients with underlying lung disease.
Mor Rubinstein, Rona Grossman, Israel Nissan, Mitchell J. Schwaber, Yehuda Carmeli, Hasia Kaidar-Shwartz, Zeev Dveyrin, Efrat Rorman   +7 more
doaj   +1 more source

Madrid, la ciudad quimera

Cahiers de Civilisation Espagnole Contemporaine, 2014
This article analyses how Madrid is pictured like a chimaera in the Spanish cinema at the end of the 20th century. For the protagonists in the films studied, Madrid is both a screen on which they project their dreams and a monstrous figure capable of ...
Bénédicte Brémard
doaj   +1 more source

International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass.

Journal of Hospital Infection, 2019
Mycobacterial infection-related morbidity and mortality in patients following cardiopulmonary bypass surgery is high and and there is a growing need for a consensus-based expert opinion to provide international guidance for diagnosing, preventing and ...
B. Hasse, M. Hannan, P. Keller, F. Maurer, R. Sommerstein, D. Mertz, D. Wagner, N. Fernández-hidalgo, Jim Nomura, V. Manfrin, D. Bettex, A. Conte, E. Durante-Mangoni, Tommy Hing-Cheung Tang, R. Stuart, J. Lundgren, S. Gordon, M. Jarashow, P. Schreiber, S. Niemann, T. Kohl, C. Daley, A. Stewardson, C. Whitener, Kiran M. Perkins, D. Plachouras, T. Lamagni, M. Chand, T. Freiberger, S. Zweifel, P. Sander, B. Schulthess, J. Scriven, H. Sax, J. van Ingen, C. Mestres, D. Diekema, B. Brown-Elliott, R. Wallace, L. Baddour, J. Miro, B. Hoen   +41 more
semanticscholar   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

First Australian case of disseminated Mycobacterium chimaera infection post-cardiothoracic surgery

, 2017
A 68 year old female patient was diagnosed with disseminated Mycobacterium chimaera infection 13 months following open cardiothoracic surgery that involved the insertion of a mitral annuloplasty ring.
Playford, EG, Coulter, C, Bursle, E, Griffin, P   +3 more
core   +1 more source

Identification of Mycobacterium chimaera in heater-cooler units in China [PDF]

, 2018
A global outbreak of infections due to Mycobacterium chimaera has been linked to the LivaNova (formerly Sorin) 3 T heater-cooler units (HCUs). We performed a study to investigate M. chimaera from HCUs in China.
Zhiyong Zong, Zong, Zhiyong, Feng, Yu, Zhang, Xiaoxia, Alan McNally, Yu Feng, Wang, Xiaohui, McNally, Alan; id_orcid, Xiaohui Wang, Lin, Ji, Ji Lin, Xiaoxia Zhang   +11 more
core   +1 more source

Occurrence and Clinical Relevance of Mycobacterium chimaera sp. nov., Germany

Emerging Infectious Diseases, 2008
Retrospective molecular genetic analysis of 166 Mycobacterium intracellulare isolates showed that 143 (86%) strains could be assigned to Mycobacterium chimaera sp. nov. Of 97 patients from whom M. chimaera sp. nov.
Birgitta Schweickert, Oliver Goldenberg, Elvira Richter, Ulf B. Göbel, Annette Petrich, Petra Buchholz, Annette Moter   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source