Results 11 to 20 of about 136,848 (282)

Chimera: Efficiently Training Large-Scale Neural Networks with Bidirectional Pipelines [PDF]

open access: yesInternational Conference for High Performance Computing, Networking, Storage and Analysis, 2021
Training large deep learning models at scale is very challenging. This paper proposes Chimera, a novel pipeline parallelism scheme which combines bidirectional pipelines for efficiently training large-scale models.
Shigang Li, T. Hoefler
semanticscholar   +1 more source

Higher-order interactions promote chimera states. [PDF]

open access: yesPhysical Review E, 2022
Since the discovery of chimera states, the presence of a nonzero phase lag parameter turns out to be an essential attribute for the emergence of chimeras in a nonlocally coupled identical Kuramoto phase oscillators' network with pairwise interactions. In
Srilena Kundu, D. Ghosh
semanticscholar   +1 more source

The changing notion of chimera states, a critical review [PDF]

open access: yes, 2021
Chimera states, states of coexistence of synchronous and asynchronous motion, have been a subject of extensive research since they were first given a name in 2004.
Sindre W. Haugland
semanticscholar   +1 more source

Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy

open access: yesJournal of Hematology & Oncology, 2020
Proteolysis-targeting chimera (PROTAC) has been developed to be a useful technology for targeted protein degradation. A bifunctional PROTAC molecule consists of a ligand (mostly small-molecule inhibitor) of the protein of interest (POI) and a covalently ...
Xin Li, Yongcheng Song
semanticscholar   +1 more source

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

open access: yesNature Communications, 2020
Small molecules that selectively kill senescent cells (SCs), termed senolytics, have the potential to prevent and treat various age-related diseases and extend healthspan.
Yonghan He   +21 more
semanticscholar   +1 more source

Molecular Docking Using Chimera and Autodock Vina Software for Nonbioinformaticians

open access: yesJMIR Bioinformatics and Biotechnology, 2020
In the field of drug discovery, many methods of molecular modeling have been employed to study complex biological and chemical systems. Experimental strategies are integrated with computational approaches for the identification, characterization, and ...
S. Butt   +3 more
semanticscholar   +1 more source

Chimera states in hybrid coupled neuron populations [PDF]

open access: yesNeural Networks, 2020
Here we study the emergence of chimera states, a recently reported phenomenon referring to the coexistence of synchronized and unsynchronized dynamical units, in a population of Morris-Lecar neurons which are coupled by both electrical and chemical ...
Ali Calim   +3 more
semanticscholar   +1 more source

UCHIME improves sensitivity and speed of chimera detection

open access: yesBioinform., 2011
Motivation: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single regions (e.g. 16S rRNA or fungal Internal Transcribed Spacer) to assess diversity or compare populations.
Robert C Edgar   +4 more
semanticscholar   +1 more source

Characteristics of Chimeric West Nile Virus Based on the Japanese Encephalitis Virus SA14-14-2 Backbone

open access: yesViruses, 2021
West Nile virus disease (WND) is an arthropod-borne zoonosis responsible for nonspecific fever or severe encephalitis. The pathogen is West Nile virus belonging to the genus Flavivirus, family Flaviviridae.
Guohua Li   +20 more
doaj   +1 more source

Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB

open access: yesApplied and Environmental Microbiology, 2006
A 16S rRNA gene database (http://greengenes.lbl.gov ) addresses limitations of public repositories by providing chimera screening, standard alignment, and taxonomic classification using multiple published taxonomies.
T. DeSantis   +9 more
semanticscholar   +1 more source

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