Results 91 to 100 of about 115,586 (310)

Control of Chimera States in Multilayer Networks [PDF]

open access: yesFrontiers in Applied Mathematics and Statistics, 2019
Chimera states are intriguing complex spatio-temporal patterns of coexisting coherent and incoherent domains. They can often be observed in networks with non-local coupling topology, where each element interacts with its neighbors within a fixed range.
Iryna Omelchenko   +3 more
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Gene Modification in Non-Human Animal for Developing Human Compatible Organs: Ethical, Legal, Clinical and Societal Issues

open access: yesBangladesh Journal of Bioethics, 2023
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) as a gene editing tool is a precise and promising technology. By CRISPR technology, human gene can be introduced into the animal gene pool to develop chimera for human like cells/tissue.
Arif Jamil   +3 more
doaj   +1 more source

Birth and Death of Chimera: Interplay of Delay and Multiplexing

open access: yes, 2016
The chimera state with co-existing coherent-incoherent dynamics has recently attracted a lot of attention due to its wide applicability. We investigate non-locally coupled identical chaotic maps with delayed interactions in the multiplex network ...
Ghosh, Saptarshi   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Chimera states: Coexistence of coherence and incoherence in networks of coupled oscillators

open access: yes, 2015
A chimera state is a spatio-temporal pattern in a network of identical coupled oscillators in which synchronous and asynchronous oscillation coexist.
Abrams, Daniel M., Panaggio, Mark J.
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Is repulsion good for the health of Chimeras?

open access: yes, 2017
Yes! Very much so. A chimera state refers to the coexistence of a coherent-incoherent dynamical evolution of identically coupled oscillators. We investigate the impact of multiplexing of a lyer having repulsively coupled oscillators on occurrence of ...
Ghosh, Saptarshi   +2 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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