Results 81 to 90 of about 90,300 (269)

Fractal basins as a mechanism for the nimble brain

open access: yesScientific Reports, 2023
An interesting feature of the brain is its ability to respond to disparate sensory signals from the environment in unique ways depending on the environmental context or current brain state. In dynamical systems, this is an example of multi-stability, the
Erik Bollt   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Twisted chimera states and multicore spiral chimera states on a two-dimensional torus

open access: yesPhysical Review E, 2015
Chimera states consisting of domains of coherently and incoherently oscillating oscillators in a two-dimensional periodic array of nonlocally coupled phase oscillators are studied. In addition to the one-dimensional chimera states familiar from one spatial dimension, two-dimensional structures termed twisted chimera states and spiral wave chimera ...
Jianbo, Xie   +2 more
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Chimerapedia: coherence–incoherence patterns in one, two and three dimensions

open access: yesNew Journal of Physics, 2019
Chimera states, or coherence–incoherence patterns in systems of symmetrically coupled identical oscillators, have been the subject of intensive study for the last two decades.
Oleh E Omel’chenko, Edgar Knobloch
doaj   +1 more source

Directed Flow of Information in Chimera States

open access: yesFrontiers in Applied Mathematics and Statistics, 2019
We investigated interactions within chimera states in a phase oscillator network with two coupled subpopulations. To quantify interactions within and between these subpopulations, we estimated the corresponding (delayed) mutual information that—in ...
Nicolás Deschle   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Influence of additive noise on chimera and solitary states in neural networks [PDF]

open access: yesИзвестия высших учебных заведений: Прикладная нелинейная динамика
The purpose of this work is to study numerically the influence of additive white Gaussian noise on the dynamics of a network of nonlocally coupled neuron models which are represented by FitzHugh–Nagumo oscillators.
Ryabchenko, Andrey Дмитриевич   +2 more
doaj   +1 more source

Engineering chimera patterns in networks using heterogeneous delays

open access: yes, 2018
Symmetry breaking spatial patterns, referred to as chimera states, have recently been catapulted into the limelight due to their coexisting coherent and incoherent hybrid dynamics.
Ghosh, Saptarshi, Jalan, Sarika
core   +1 more source

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