Results 191 to 200 of about 150,649 (280)

Xanthatin‐13‐(Pyrrolidine‐2‐Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ25‐35 Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2824-2843, May 2026.
ABSTRACT Alzheimer's disease (AD) is a severe form of dementia, which occurrence increases with age and lifestyle conditions. It is characterized by amyloid protein accumulation forming senile plaques, hyperphosphorylated tau protein forming neurofibrillary tangles, neuroinflammation, and oxidative stress, leading to synapse loss and cell death ...
Charlyne Barry‐Simonnet   +10 more
wiley   +1 more source

Non‐Covalent Interactions Enable Hierarchical Self‐Assembly in TeTrazine‐Bearing Systems: From Soft Matter to Mesogens

open access: yesChemSystemsChem, Volume 8, Issue 3, May 2026.
This study focuses on the supramolecular self‐assembly of a newly developed family of compounds featuring s‐tetrazine. In particular, we highlight structure‐property relations and how gelation and mesogenic properties can be directed as a consequence of different side chains introduced in the system.
Lucrezia Trevisan   +9 more
wiley   +1 more source

Synthesis of Conjugated Linear and Cyclic Polyynes by Selective Alkyne Metathesis

open access: yesAngewandte Chemie, Volume 138, Issue 17, 20 April 2026.
The formation of polyynes with an odd number of conjugated triple bonds is challenging, particularly for complex architectures since most established methods rely on irreversible C–C bond‐forming reactions. To address this, we have developed the synthesis of triynes via alkyne metathesis.
Julien Escudero   +12 more
wiley   +2 more sources

Soft X‐rays with orbital angular momentum for resonant scattering experiments at Synchrotron SOLEIL

open access: yesJournal of Synchrotron Radiation, Volume 33, Issue 3, Page 858-869, May 2026.
Characterization and testing of a new setup for absorption and scattering experiments with soft X‐rays carrying an orbital angular momentum at the SEXTANTS beamline of Synchrotron SOLEIL are presented.The paper presents a comprehensive description of a new setup implemented and commissioned at the SEXTANTS beamline of Synchrotron SOLEIL for absorption ...
Pietro Carrara   +17 more
wiley   +1 more source

Extended Fused Carbazole‐BODIPY, High Brightness NIR Organic Dyes

open access: yesAngewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Highly fused boron‐dipyrromethene (BODIPY) with a strong donor group has been synthesized, and their photophysical behaviors fully characterized. They exhibit outstanding brightness for fluorophores emitting in the NIR region. Water‐soluble nanoparticles filled with one of these dyes demonstrate high efficiency as the NIR II visualization agent ...
Fabien Ceugniet   +9 more
wiley   +2 more sources

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2307-2323, May 2026.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert   +13 more
wiley   +1 more source

Efficient Microwave-Assisted Hydrolytic Recycling of Poly(L-Lactic Acid). [PDF]

open access: yesChemSusChem
Santulli F   +6 more
europepmc   +1 more source

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