Results 91 to 100 of about 34,442 (247)
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer +5 more
wiley +1 more source
Lithic analysis in African archaeology: Advances and key themes
Abstract Stone artifacts (lithics) preserve for extended periods; thus they are key evidence for probing the evolution of human technological behaviors. Africa boasts the oldest record of stone artifacts, spanning 3.3 Ma, rare instances of ethnographic stone tool‐making, and stone tool archives from diverse ecological settings, making it an anchor for ...
Deborah I. Olszewski +2 more
wiley +1 more source
Investigating relationships among strontium, barium, and seasonality in wild baboons
Abstract Geochemical profiles of Australopithecus africanus and baboon teeth show fluctuating trace elements, possibly reflecting seasonal diets. Here we use laser ablation–inductively coupled plasma–mass spectrometric measurements of calcium‐normalized strontium and barium ratios (Sr/Ca and Ba/Ca) and ion microprobe analyses of oxygen isotopes (δ18O ...
Maya Bharatiya +12 more
wiley +1 more source
Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith +5 more
wiley +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
ABSTRACT We situate this article from/with/in the Necrocene, a geological period marked by the systematic production of human and more‐than‐human death to an extent that ecological destruction, extinction, loss and harm have become a structural feature of modern life.
Charlotte Hankin, Hannah Hogarth
wiley +1 more source
Honouring Hardship and Fun: Reflecting on Homeless Children's Experiences in Shelter
ABSTRACT In our research with children living in a homeless shelter with their families in Southern Ontario, Canada, we navigated discrepancies between the challenges and hardships in our participants' lives and the fun, positive nature of many of our day‐to‐day interactions with them.
Rebecca Raby +4 more
wiley +1 more source
Abstract Monitoring wildlife health is essential for conservation and management, wildlife and livestock welfare, and public health in a One Health framework. Yet, wildlife health monitoring often requires long‐term fieldwork and intensive sampling, which can be costly or logistically challenging, especially for remote, rare, or elusive populations. To
Jonathan Tichon +8 more
wiley +1 more source

